diff --git a/vllm/model_executor/models/qwen2_5_vl.py b/vllm/model_executor/models/qwen2_5_vl.py
index c4c4650f56..04e64422d2 100644
--- a/vllm/model_executor/models/qwen2_5_vl.py
+++ b/vllm/model_executor/models/qwen2_5_vl.py
@@ -43,9 +43,10 @@ from vllm.distributed import parallel_state
 from vllm.distributed import utils as dist_utils
 from vllm.logger import init_logger
 from vllm.model_executor import SamplingMetadata
-from vllm.model_executor.layers.activation import _ACTIVATION_REGISTRY
+from vllm.model_executor.layers.activation import get_act_and_mul_fn
 from vllm.model_executor.layers.layernorm import RMSNorm
 from vllm.model_executor.layers.linear import (ColumnParallelLinear,
+                                               MergedColumnParallelLinear,
                                                QKVParallelLinear,
                                                RowParallelLinear)
 from vllm.model_executor.layers.quantization import QuantizationConfig
@@ -171,16 +172,12 @@ class Qwen2_5_VisionMLP(nn.Module):
                  quant_config: Optional[QuantizationConfig] = None,
                  prefix: str = ""):
         super().__init__()
-        self.gate_proj = ColumnParallelLinear(in_features,
-                                              hidden_features,
-                                              bias=bias,
-                                              quant_config=quant_config,
-                                              prefix=f"{prefix}.gate_proj")
-        self.up_proj = ColumnParallelLinear(in_features,
-                                            hidden_features,
-                                            bias=bias,
-                                            quant_config=quant_config,
-                                            prefix=f"{prefix}.up_proj")
+        self.gate_up_proj = MergedColumnParallelLinear(
+            input_size=in_features,
+            output_sizes=[hidden_features] * 2,  # [gate_proj, up_proj]
+            bias=bias,
+            quant_config=quant_config,
+            prefix=f"{prefix}.gate_up_proj")
         self.down_proj = RowParallelLinear(hidden_features,
                                            in_features,
                                            bias=bias,
@@ -189,10 +186,9 @@ class Qwen2_5_VisionMLP(nn.Module):
         self.act_fn = act_fn
 
     def forward(self, x: torch.Tensor):
-        x_gate, _ = self.gate_proj(x)
-        x_gate = self.act_fn(x_gate)
-        x_up, _ = self.up_proj(x)
-        x_down, _ = self.down_proj(x_gate * x_up)
+        gate_up, _ = self.gate_up_proj(x)
+        x = self.act_fn(gate_up)
+        x_down, _ = self.down_proj(x)
         return x_down
 
 
@@ -540,14 +536,14 @@ class Qwen2_5_VisionTransformer(nn.Module):
         self.rotary_pos_emb = Qwen2_5_VisionRotaryEmbedding(head_dim // 2)
 
         self.blocks = nn.ModuleList([
-            Qwen2_5_VisionBlock(
-                dim=self.hidden_size,
-                num_heads=self.num_heads,
-                mlp_hidden_dim=vision_config.intermediate_size,
-                act_fn=_ACTIVATION_REGISTRY[vision_config.hidden_act],
-                norm_layer=norm_layer,
-                quant_config=quant_config,
-                prefix=f"{prefix}.blocks.{layer_idx}")
+            Qwen2_5_VisionBlock(dim=self.hidden_size,
+                                num_heads=self.num_heads,
+                                mlp_hidden_dim=vision_config.intermediate_size,
+                                act_fn=get_act_and_mul_fn(
+                                    vision_config.hidden_act),
+                                norm_layer=norm_layer,
+                                quant_config=quant_config,
+                                prefix=f"{prefix}.blocks.{layer_idx}")
             for layer_idx in range(depth)
         ])
         self.merger = Qwen2_5_VisionPatchMerger(
@@ -752,6 +748,8 @@ class Qwen2_5_VisionTransformer(nn.Module):
             ("attn.qkv.", "attn.q.", "q"),
             ("attn.qkv.", "attn.k.", "k"),
             ("attn.qkv.", "attn.v.", "v"),
+            ("mlp.gate_up_proj.", "mlp.gate_proj.", 0),
+            ("mlp.gate_up_proj.", "mlp.up_proj.", 1),
         ]
         params_dict = dict(self.named_parameters(remove_duplicate=False))
         loaded_params: set[str] = set()