diff --git a/.ci/pytorch/test.sh b/.ci/pytorch/test.sh
index 9ca0decd087e..3e2dc09ef495 100755
--- a/.ci/pytorch/test.sh
+++ b/.ci/pytorch/test.sh
@@ -485,6 +485,22 @@ test_inductor_aoti() {
   /usr/bin/env "${TEST_ENVS[@]}" python test/run_test.py --cpp --verbose -i cpp/test_aoti_abi_check cpp/test_aoti_inference cpp/test_vec_half_AVX2 -dist=loadfile
 }
 
+test_inductor_aoti_cross_compile_for_windows() {
+
+  TEST_REPORTS_DIR=$(pwd)/test/test-reports
+  mkdir -p "$TEST_REPORTS_DIR"
+
+  # Set WINDOWS_CUDA_HOME environment variable
+  WINDOWS_CUDA_HOME="$(pwd)/win-torch-wheel-extracted"
+  export WINDOWS_CUDA_HOME
+
+  echo "WINDOWS_CUDA_HOME is set to: $WINDOWS_CUDA_HOME"
+  echo "Contents:"
+  ls -lah "$(pwd)/win-torch-wheel-extracted/lib/x64/" || true
+
+  python test/inductor/test_aoti_cross_compile_windows.py -k compile --package-dir "$TEST_REPORTS_DIR" --win-torch-lib-dir "$(pwd)/win-torch-wheel-extracted/torch/lib"
+}
+
 test_inductor_cpp_wrapper_shard() {
   if [[ -z "$NUM_TEST_SHARDS" ]]; then
     echo "NUM_TEST_SHARDS must be defined to run a Python test shard"
@@ -1718,6 +1734,8 @@ elif [[ "${TEST_CONFIG}" == *inductor-triton-cpu* ]]; then
   test_inductor_triton_cpu
 elif [[ "${TEST_CONFIG}" == *inductor-micro-benchmark* ]]; then
   test_inductor_micro_benchmark
+elif [[ "${TEST_CONFIG}" == *aoti_cross_compile_for_windows* ]]; then
+  test_inductor_aoti_cross_compile_for_windows
 elif [[ "${TEST_CONFIG}" == *huggingface* ]]; then
   install_torchvision
   id=$((SHARD_NUMBER-1))
diff --git a/.github/workflows/_linux-test.yml b/.github/workflows/_linux-test.yml
index 89f13d3fea8f..29c2fc8e0847 100644
--- a/.github/workflows/_linux-test.yml
+++ b/.github/workflows/_linux-test.yml
@@ -224,6 +224,46 @@ jobs:
         continue-on-error: true
         uses: ./.github/actions/download-td-artifacts
 
+      - name: Download Windows torch wheel for cross-compilation
+        if: matrix.win_torch_wheel_artifact != ''
+        uses: seemethere/download-artifact-s3@1da556a7aa0a088e3153970611f6c432d58e80e6 # v4.2.0
+        with:
+          name: ${{ matrix.win_torch_wheel_artifact }}
+          path: win-torch-wheel
+
+      - name: Extract Windows wheel and setup CUDA libraries
+        if: matrix.win_torch_wheel_artifact != ''
+        shell: bash
+        run: |
+          set -x
+
+          # Find the wheel file
+          WHEEL_FILE=$(find win-torch-wheel -name "*.whl" -type f | head -n 1)
+          if [ -z "$WHEEL_FILE" ]; then
+            echo "Error: No wheel file found in win-torch-wheel directory"
+            exit 1
+          fi
+          echo "Found wheel file: $WHEEL_FILE"
+
+          # Unzip the wheel file
+          unzip -q "$WHEEL_FILE" -d win-torch-wheel-extracted
+          echo "Extracted wheel contents"
+
+          # Setup CUDA libraries (cuda.lib and cudart.lib) directory
+          mkdir -p win-torch-wheel-extracted/lib/x64
+          if [ -f "win-torch-wheel/cuda.lib" ]; then
+            mv win-torch-wheel/cuda.lib win-torch-wheel-extracted/lib/x64/
+            echo "Moved cuda.lib to win-torch-wheel-extracted/lib/x64/"
+          fi
+          if [ -f "win-torch-wheel/cudart.lib" ]; then
+            mv win-torch-wheel/cudart.lib win-torch-wheel-extracted/lib/x64/
+            echo "Moved cudart.lib to win-torch-wheel-extracted/lib/x64/"
+          fi
+
+          # Verify CUDA libraries are present
+          echo "CUDA libraries:"
+          ls -la win-torch-wheel-extracted/lib/x64/ || echo "No CUDA libraries found"
+
       - name: Parse ref
         id: parse-ref
         run: .github/scripts/parse_ref.py
diff --git a/.github/workflows/_win-build.yml b/.github/workflows/_win-build.yml
index 153f6007b3f0..0fd3cf7f3972 100644
--- a/.github/workflows/_win-build.yml
+++ b/.github/workflows/_win-build.yml
@@ -168,6 +168,31 @@ jobs:
         run: |
           .ci/pytorch/win-build.sh
 
+      # Collect Windows torch libs and CUDA libs for cross-compilation
+      - name: Collect Windows CUDA libs for cross-compilation
+        if: steps.build.outcome != 'skipped' && inputs.cuda-version != 'cpu'
+        shell: bash
+        run: |
+          set -ex
+
+          # Create directory structure if does not exist
+          mkdir -p /c/${{ github.run_id }}/build-results
+
+          # Copy CUDA libs
+          CUDA_PATH="/c/Program Files/NVIDIA GPU Computing Toolkit/CUDA/v${{ inputs.cuda-version }}"
+
+          if [ -f "${CUDA_PATH}/lib/x64/cuda.lib" ]; then
+            cp "${CUDA_PATH}/lib/x64/cuda.lib" /c/${{ github.run_id }}/build-results/
+          fi
+
+          if [ -f "${CUDA_PATH}/lib/x64/cudart.lib" ]; then
+            cp "${CUDA_PATH}/lib/x64/cudart.lib" /c/${{ github.run_id }}/build-results/
+          fi
+
+          # List collected files
+          echo "Collected CUDA libs:"
+          ls -lah /c/${{ github.run_id }}/build-results/*.lib
+
       # Upload to github so that people can click and download artifacts
       - name: Upload artifacts to s3
         if: steps.build.outcome != 'skipped'
diff --git a/.github/workflows/trunk.yml b/.github/workflows/trunk.yml
index c8aab0aee10e..710b6cfa9eaf 100644
--- a/.github/workflows/trunk.yml
+++ b/.github/workflows/trunk.yml
@@ -200,6 +200,23 @@ jobs:
       cuda-arch-list: '8.0'
     secrets: inherit
 
+  # Test cross-compiled models with Windows libs extracted from wheel
+  cross-compile-linux-test:
+    name: cross-compile-linux-test
+    uses: ./.github/workflows/_linux-test.yml
+    needs:
+      - linux-jammy-cuda12_8-py3_10-gcc11-build
+      - get-label-type
+      - win-vs2022-cuda12_8-py3-build
+    with:
+      build-environment: linux-jammy-cuda12.8-py3.10-gcc11
+      docker-image: ${{ needs.linux-jammy-cuda12_8-py3_10-gcc11-build.outputs.docker-image }}
+      test-matrix: |
+        { include: [
+          { config: "aoti_cross_compile_for_windows", shard: 1, num_shards: 1, runner: "${{ needs.get-label-type.outputs.label-type }}linux.g6.4xlarge.experimental.nvidia.gpu", win_torch_wheel_artifact: "win-vs2022-cuda12.8-py3" },
+        ]}
+    secrets: inherit
+
   verify-cachebench-cpu-build:
     name: verify-cachebench-cpu-build
     uses: ./.github/workflows/_linux-build.yml
diff --git a/test/inductor/test_aoti_cross_compile_windows.py b/test/inductor/test_aoti_cross_compile_windows.py
new file mode 100644
index 000000000000..04065add9081
--- /dev/null
+++ b/test/inductor/test_aoti_cross_compile_windows.py
@@ -0,0 +1,371 @@
+# Owner(s): ["module: inductor"]
+import os
+import platform
+import tempfile
+import unittest
+from dataclasses import dataclass
+from pathlib import Path
+from typing import Any, Optional
+
+import torch
+import torch._inductor.config
+from torch._inductor.test_case import TestCase
+from torch.testing._internal.inductor_utils import GPU_TYPE, HAS_GPU, requires_gpu
+
+
+@dataclass
+class ModelTestConfig:
+    """Configuration for a model test case."""
+
+    name: str
+    model_class: type
+    example_inputs: tuple[torch.Tensor, ...]
+    dynamic_shapes: Optional[dict[str, Any]] = None
+    inductor_configs: Optional[dict[str, Any]] = None
+    rtol: float = 1e-4
+    atol: float = 1e-4
+
+
+class WindowsCrossCompilationTestFramework:
+    """
+    Framework for testing cross-compilation from Linux to Windows.
+
+    Provides reusable logic for creating compile and load test methods.
+    """
+
+    _base_path: Optional[Path] = None
+    _win_torch_libs_path: Optional[str] = None
+
+    @classmethod
+    def base_path(cls) -> Path:
+        """Get or create the base path for package files."""
+        if cls._base_path is None:
+            cls._base_path = Path(tempfile.mkdtemp(prefix="aoti_cross_compile_"))
+        return cls._base_path
+
+    @classmethod
+    def set_base_path(cls, path: Optional[Path | str] = None) -> None:
+        """Set the base path for package files."""
+        cls._base_path = Path(path) if path else None
+
+    @classmethod
+    def set_win_torch_libs_path(cls, path: Optional[str] = None) -> None:
+        """Set the path for Windows torch libs."""
+        cls._win_torch_libs_path = path
+
+    @classmethod
+    def get_package_path(cls, model_name: str) -> str:
+        """Get the path for a model's .pt2 package file."""
+        package_dir = cls.base_path()
+        package_dir.mkdir(parents=True, exist_ok=True)
+        return str(package_dir / f"{model_name}_windows.pt2")
+
+    @classmethod
+    def get_win_torch_libs_path(cls) -> str:
+        """Get the path for Windows torch libs."""
+        if cls._win_torch_libs_path is None:
+            raise RuntimeError("Windows torch libs path not set")
+        return str(cls._win_torch_libs_path)
+
+    @classmethod
+    def create_compile_test(cls, config: ModelTestConfig):
+        """Create a compile test method for a model configuration."""
+
+        def compile_test(self):
+            if platform.system() == "Windows":
+                raise unittest.SkipTest(
+                    "This test should run on Linux for cross-compilation"
+                )
+
+            self.assertTrue("WINDOWS_CUDA_HOME" in os.environ)
+
+            with torch.no_grad():
+                # Windows cross-compilation is only used for GPU.
+                # AOTI for CPU should be able to work as native compilation on Windows.
+                device = GPU_TYPE
+                model = config.model_class().to(device=device)
+                example_inputs = config.example_inputs
+
+                # Inputs should already be on GPU_TYPE but ensure they are
+                example_inputs = tuple(inp.to(device) for inp in example_inputs)
+
+                # Export the model
+                exported = torch.export.export(
+                    model, example_inputs, dynamic_shapes=config.dynamic_shapes
+                )
+
+                # Prepare inductor configs
+                inductor_configs = {
+                    "aot_inductor.cross_target_platform": "windows",
+                    "aot_inductor.precompile_headers": False,
+                    "aot_inductor.package_constants_on_disk_format": "binary_blob",
+                    "aot_inductor.package_constants_in_so": False,
+                    "aot_inductor.aoti_shim_library_path": cls.get_win_torch_libs_path(),
+                }
+                if config.inductor_configs:
+                    inductor_configs.update(config.inductor_configs)
+
+                # Compile and package directly to the expected location
+                package_path = cls.get_package_path(config.name)
+                torch._inductor.aoti_compile_and_package(
+                    exported,
+                    package_path=package_path,
+                    inductor_configs=inductor_configs,
+                )
+
+                self.assertTrue(
+                    os.path.exists(package_path),
+                    f"Package file should exist at {package_path}",
+                )
+
+        return compile_test
+
+    @classmethod
+    def create_load_test(cls, config: ModelTestConfig):
+        """Create a load test method for a model configuration."""
+
+        def load_test(self):
+            if platform.system() != "Windows":
+                raise unittest.SkipTest("This test should run on Windows")
+
+            if not HAS_GPU:
+                raise unittest.SkipTest("Test requires GPU")
+
+            package_path = cls.get_package_path(config.name)
+            if not os.path.exists(package_path):
+                raise unittest.SkipTest(
+                    f"Package file not found at {package_path}. "
+                    f"Run test_{config.name}_compile first."
+                )
+
+            with torch.no_grad():
+                # Windows cross-compilation is only used for GPU.
+                # AOTI for CPU should be able to work as native compilation on Windows.
+                device = GPU_TYPE
+
+                # Create original model for comparison
+                original_model = config.model_class().to(device=device)
+                example_inputs = config.example_inputs
+
+                # Inputs should already be on GPU_TYPE but ensure they are
+                example_inputs = tuple(inp.to(device) for inp in example_inputs)
+
+                # Load the compiled package
+                loaded_model = torch._inductor.aoti_load_package(package_path)
+
+                # Test with the same inputs
+                original_output = original_model(*example_inputs)
+                loaded_output = loaded_model(*example_inputs)
+
+                # Compare outputs
+                torch.testing.assert_close(
+                    original_output, loaded_output, rtol=config.rtol, atol=config.atol
+                )
+
+        return load_test
+
+
+def auto_generate_tests(test_class):
+    """
+    Class decorator to automatically generate compile/load test methods
+    from _define_* methods that return ModelTestConfig.
+    """
+    # Find all _define_* methods that return ModelTestConfig
+    define_methods = {}
+    for name in dir(test_class):
+        if name.startswith("_define_") and callable(getattr(test_class, name)):
+            method = getattr(test_class, name)
+            # Try to call the method to see if it returns ModelTestConfig
+            try:
+                # Create a temporary instance to call the method
+                temp_instance = test_class.__new__(test_class)
+                result = method(temp_instance)
+                if isinstance(result, ModelTestConfig):
+                    define_methods[name] = result
+            except Exception:
+                # If method fails, skip it
+                pass
+
+    # Generate compile/load methods for each discovered definition
+    for define_name, config in define_methods.items():
+        model_name = define_name[8:]  # Remove '_define_' prefix
+
+        # Create compile test method
+        compile_method_name = f"test_{model_name}_compile"
+        compile_method = WindowsCrossCompilationTestFramework.create_compile_test(
+            config
+        )
+        compile_method.__name__ = compile_method_name
+        compile_method.__doc__ = f"Step 1: Cross-compile {model_name} model on Linux"
+        compile_method = requires_gpu()(compile_method)
+        setattr(test_class, compile_method_name, compile_method)
+
+        # Create load test method
+        load_method_name = f"test_{model_name}_load"
+        load_method = WindowsCrossCompilationTestFramework.create_load_test(config)
+        load_method.__name__ = load_method_name
+        load_method.__doc__ = f"Step 2: Load and test {model_name} model on Windows"
+        load_method = requires_gpu()(load_method)
+        setattr(test_class, load_method_name, load_method)
+
+    return test_class
+
+
+@auto_generate_tests
+class TestAOTInductorWindowsCrossCompilation(TestCase):
+    """
+    Test class for AOT Inductor Windows cross-compilation.
+
+    Define test methods that return ModelTestConfig, and the decorator
+    will auto-generate compile/load test methods.
+    """
+
+    def _define_simple(self):
+        """Define the Simple model and its test configuration."""
+
+        class Simple(torch.nn.Module):
+            def __init__(self):
+                super().__init__()
+                self.fc1 = torch.nn.Linear(10, 16)
+                self.relu = torch.nn.ReLU()
+                self.fc2 = torch.nn.Linear(16, 1)
+                self.sigmoid = torch.nn.Sigmoid()
+
+            def forward(self, x):
+                x = self.fc1(x)
+                x = self.relu(x)
+                x = self.fc2(x)
+                x = self.sigmoid(x)
+                return x
+
+        return ModelTestConfig(
+            name="simple",
+            model_class=Simple,
+            example_inputs=(torch.randn(8, 10, device=GPU_TYPE),),
+            dynamic_shapes={"x": {0: torch.export.Dim("batch", min=1, max=1024)}},
+        )
+
+    def _define_simple_cnn(self):
+        """Define the SimpleCNN model and its test configuration."""
+
+        class SimpleCNN(torch.nn.Module):
+            def __init__(self):
+                super().__init__()
+                self.conv1 = torch.nn.Conv2d(3, 16, 3)
+                self.relu = torch.nn.ReLU()
+                self.pool = torch.nn.AdaptiveAvgPool2d((1, 1))
+                self.fc = torch.nn.Linear(16, 10)
+
+            def forward(self, x):
+                x = self.conv1(x)
+                x = self.relu(x)
+                x = self.pool(x)
+                x = x.flatten(1)
+                x = self.fc(x)
+                return x
+
+        return ModelTestConfig(
+            name="simple_cnn",
+            model_class=SimpleCNN,
+            example_inputs=(torch.randn(2, 3, 32, 32, device=GPU_TYPE),),
+            dynamic_shapes={"x": {0: torch.export.Dim("batch", min=1, max=16)}},
+            rtol=1e-3,
+            atol=1e-3,
+        )
+
+    def _define_transformer(self):
+        """Define the SimpleTransformer model and its test configuration."""
+
+        class SimpleTransformer(torch.nn.Module):
+            def __init__(self):
+                super().__init__()
+                self.embedding = torch.nn.Linear(128, 256)
+                self.attention = torch.nn.MultiheadAttention(256, 8, batch_first=True)
+                self.norm1 = torch.nn.LayerNorm(256)
+                self.ffn = torch.nn.Sequential(
+                    torch.nn.Linear(256, 1024),
+                    torch.nn.ReLU(),
+                    torch.nn.Linear(1024, 256),
+                )
+                self.norm2 = torch.nn.LayerNorm(256)
+                self.output = torch.nn.Linear(256, 10)
+
+            def forward(self, x):
+                # x shape: (batch, seq_len, input_dim)
+                x = self.embedding(x)
+                attn_out, _ = self.attention(x, x, x)
+                x = self.norm1(x + attn_out)
+                ffn_out = self.ffn(x)
+                x = self.norm2(x + ffn_out)
+                x = x.mean(dim=1)  # Global average pooling
+                x = self.output(x)
+                return x
+
+        return ModelTestConfig(
+            name="transformer",
+            model_class=SimpleTransformer,
+            example_inputs=(torch.randn(4, 16, 128, device=GPU_TYPE),),
+            dynamic_shapes={"x": {0: torch.export.Dim("batch", min=1, max=32)}},
+            rtol=1e-3,
+            atol=1e-3,
+        )
+
+
+if __name__ == "__main__":
+    import sys
+
+    from torch._inductor.test_case import run_tests
+
+    # Check for --package-dir argument and remove it before unittest sees it
+    package_dir = None
+    win_torch_lib_dir = None
+    filtered_argv = []
+    i = 0
+    while i < len(sys.argv):
+        if sys.argv[i] == "--package-dir":
+            if i + 1 < len(sys.argv):
+                package_dir = sys.argv[i + 1]
+                i += 2  # Skip both --package-dir and its value
+            else:
+                print("Error: --package-dir requires a valid directory path")
+                sys.exit(1)
+        elif sys.argv[i].startswith("--package-dir="):
+            package_dir = sys.argv[i].split("=", 1)[1]
+            i += 1
+        elif sys.argv[i] == "--win-torch-lib-dir":
+            if i + 1 < len(sys.argv):
+                win_torch_lib_dir = sys.argv[i + 1]
+                i += 2  # Skip both --win-torch-lib-dir and its value
+            else:
+                print("Error: --win-torch-lib-dir requires a valid directory path")
+                sys.exit(1)
+        elif sys.argv[i].startswith("--win-torch-lib-dir="):
+            win_torch_lib_dir = sys.argv[i].split("=", 1)[1]
+            i += 1
+        else:
+            filtered_argv.append(sys.argv[i])
+            i += 1
+
+    # Validate and set the base path for package storage
+    if package_dir:
+        try:
+            package_path = Path(package_dir)
+            package_path.mkdir(parents=True, exist_ok=True)
+            # Test write access
+            test_file = package_path / ".test_write"
+            test_file.touch()
+            test_file.unlink()
+            WindowsCrossCompilationTestFramework.set_base_path(package_path)
+        except Exception:
+            print("Error: --package-dir requires a valid directory path")
+            sys.exit(1)
+
+    # Set Windows torch libs path if provided (only needed for compile tests)
+    if win_torch_lib_dir:
+        WindowsCrossCompilationTestFramework.set_win_torch_libs_path(win_torch_lib_dir)
+
+    # Update sys.argv to remove our custom arguments
+    sys.argv = filtered_argv
+
+    if HAS_GPU:
+        run_tests(needs="filelock")
diff --git a/tools/testing/discover_tests.py b/tools/testing/discover_tests.py
index 13511b1ec129..1210326a02db 100644
--- a/tools/testing/discover_tests.py
+++ b/tools/testing/discover_tests.py
@@ -107,6 +107,7 @@ TESTS = discover_tests(
         "lazy/test_meta_kernel",
         "lazy/test_extract_compiled_graph",
         "test/inductor/test_aot_inductor_utils",
+        "inductor/test_aoti_cross_compile_windows",
         "onnx/test_onnxscript_no_runtime",
         "onnx/test_pytorch_onnx_onnxruntime_cuda",
         "onnx/test_models",