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PubMed file with multi-line MESH terms (MH lines).
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Tests/Medline/pubmed_result3.txt
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PMID- 23039619
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OWN - NLM
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STAT- MEDLINE
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DA - 20121008
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DCOM- 20121205
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IS - 0094-2405 (Print)
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IS - 0094-2405 (Linking)
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VI - 39
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IP - 10
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DP - 2012 Oct
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TI - Effects of different parameters in the fast scanning method for HIFU treatment.
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PG - 5795-813
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LID - 10.1118/1.4748329 [doi]
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AB - PURPOSE: High-intensity focused ultrasound is a promising method for the
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noninvasive treatment of benign and malignant tumors. This study analyzes the
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effects of scanning path, applied power, and geometric characteristics of the
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transducer on ablation using fast scanning method, a new scanning method that
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uses high-intensity focused ultrasound at different blood perfusion levels.
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METHODS: Two transducers, six scanning paths, and three focal patterns were used
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to examine the ablation results of the fast scanning method using power densities
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from 1.35 x 10(7) Wm(3) to 4.5 x 10(7) Wm(3) and blood perfusion rates from 2 x
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10(-3) mlmls to 16 x 10(-3) mlmls. The Pennes equation was solved using the
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finite-difference time-domain method to simulate the heating procedure. RESULTS:
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Based on the results of the fast-scanning method, the different scanning paths
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exhibited small effect on the total treatment time supported by both simulation
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and least-square fit. Similar-sized lesions can result from the five different
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repeated paths, whereas a random path may lead to relative large fluctuations in
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ablation volume because of asymmetry of the lesions. Higher power levels increase
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the lesion volume and decrease the treatment time required for ablating a target
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area using the fast scanning method, whereas increased blood perfusion has the
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opposite effect on ablation volume and treatment time. A symmetric lesion can be
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produced through fast scanning method using a 65-element and a 90-element
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transducer. However, lesion production using the same operation scheme differs
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between the two transducers. CONCLUSIONS: Unlike traditional scanning methods,
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fast scanning method produces a planned lesion regardless of scanning path, as
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long as the path consists of repeated subsequences. This attribute makes fast
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scanning method an easy-operation scheme that produces relatively large symmetric
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lesions in homogeneous tissues. Applied power is the most important factor;
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however, high blood perfusion levels can limit or even hinder the full ablation
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of the target area. Therefore, tissue perfusion and transducer type should be
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given special attention to ensure the success and safety of ablation treatment.
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FAU - Qiao, Shan
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AU - Qiao S
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AD - School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai,
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People's Republic of China.
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FAU - Shen, Guofeng
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AU - Shen G
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FAU - Bai, Jingfeng
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AU - Bai J
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FAU - Chen, Yazhu
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AU - Chen Y
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LA - eng
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PT - Journal Article
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PT - Research Support, Non-U.S. Gov't
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PL - United States
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TA - Med Phys
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JT - Medical physics
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JID - 0425746
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SB - IM
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MH - Blood Circulation
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MH - High-Intensity Focused Ultrasound Ablation/adverse
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effects/instrumentation/*methods
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MH - Humans
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MH - Models, Biological
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MH - Sonication
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MH - Temperature
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MH - Time Factors
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MH - Transducers
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EDAT- 2012/10/09 06:00
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MHDA- 2012/12/10 06:00
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CRDT- 2012/10/09 06:00
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AID - 10.1118/1.4748329 [doi]
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PST - ppublish
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SO - Med Phys. 2012 Oct;39(10):5795-813. doi: 10.1118/1.4748329.
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