ID   AE017046; SV 1; circular; genomic DNA; STD; PRO; 9609 BP.
XX
AC   AE017046;
XX
DT   12-MAR-2004 (Rel. 79, Created)
DT   14-NOV-2006 (Rel. 89, Last updated, Version 5)
XX
DE   Yersinia pestis biovar Microtus str. 91001 plasmid pPCP1, complete
DE   sequence.
XX
KW   .
XX
OS   Yersinia pestis biovar Microtus str. 91001
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Yersinia.
OG   Plasmid pPCP1
XX
RN   [1]
RP   1-9609
RX   DOI; 10.1093/dnares/11.3.179.
RX   PUBMED; 15368893.
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans";
RL   DNA Res. 11(3):179-197(2004).
XX
RN   [2]
RP   1-9609
RX   DOI; 10.1128/JB.186.15.5147-5152.2004.
RX   PUBMED; 15262951.
RA   Zhou D., Tong Z., Song Y., Han Y., Pei D., Pang X., Zhai J., Li M., Cui B.,
RA   Qi Z., Jin L., Dai R., Du Z., Wang J., Guo Z., Wang J., Huang P., Yang R.;
RT   "Genetics of metabolic variations between Yersinia pestis biovars and the
RT   proposal of a new biovar, microtus";
RL   J. Bacteriol. 186(15):5147-5152(2004).
XX
RN   [3]
RP   1-9609
RA   Song Y., Tong Z., Wang L., Han Y., Zhang J., Pei D., Wang J., Zhou D.,
RA   Han Y., Pang X., Zhai J., Chen F., Qin H., Wang J., Li S., Guo Z., Ye C.,
RA   Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.;
RT   ;
RL   Submitted (24-APR-2003) to the EMBL/GenBank/DDBJ databases.
RL   The Institute of Microbiology and Epidemiology, Academy of Military Medical
RL   Sciences, No. 20, Dongdajie Street, Fengtai District, Beijing 100071,
RL   People's Republic of China
XX
DR   GR; AE017046_GR.
DR   RFAM; RF00106; RNAI.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..9609
FT                   /organism="Yersinia pestis biovar Microtus str. 91001"
FT                   /plasmid="pPCP1"
FT                   /strain="91001"
FT                   /mol_type="genomic DNA"
FT                   /note="biovar: Microtus"
FT                   /db_xref="taxon:229193"
FT   repeat_region   1..1954
FT                   /mobile_element="insertion sequence:IS100"
FT   gene            87..1109
FT                   /locus_tag="YP_pPCP01"
FT                   /old_locus_tag="pPCP01"
FT   CDS             87..1109
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="YP_pPCP01"
FT                   /old_locus_tag="pPCP01"
FT                   /product="putative transposase"
FT                   /note="similar to corresponding CDS from previously
FT                   sequenced pPCP plasmid of Yersinia pestis KIM (AF053945)
FT                   and CO92 (AL109969), also many transposase entries for
FT                   insertion sequence IS100 of Yersinia pestis. Contains
FT                   IS21-like element transposase, HTH domain
FT                   (Interpro|IPR007101)"
FT                   /db_xref="GOA:Q7ARN5"
FT                   /db_xref="InterPro:IPR017894"
FT                   /db_xref="UniProtKB/TrEMBL:Q7ARN5"
FT                   /protein_id="AAS58758.1"
FT                   /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEPP
FT                   KYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIRSL
FT                   SVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMRYDT
FT                   LETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFSPRLC
FT                   RPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVANQRKH
FT                   ETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDSFCRGVA
FT                   "
FT   gene            1106..1888
FT                   /locus_tag="YP_pPCP02"
FT                   /old_locus_tag="pPCP02"
FT   CDS             1106..1888
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="YP_pPCP02"
FT                   /old_locus_tag="pPCP02"
FT                   /product="putative ATP-binding protein"
FT                   /note="similar to corresponding CDS form previously
FT                   sequenced pPCP plasmid of Yersinia pestis KIM (AF053945)
FT                   and CO92 (AL109969), also many ATP-binding protein entries
FT                   for insertion sequence IS100 of Yersinia pestis. Contains
FT                   Chaperonin clpA/B (Interpro|IPR001270). Contains
FT                   ATP/GTP-binding site motif A (P-loop) (Interpro|IPR001687,
FT                   Molecular Function: ATP binding (GO:0005524)). Contains
FT                   Bacterial chromosomal replication initiator protein, DnaA
FT                   (Interpro|IPR001957, Molecular Function: DNA binding
FT                   (GO:0003677), Molecular Function: DNA replication origin
FT                   binding (GO:0003688), Molecular Function: ATP binding
FT                   (GO:0005524), Biological Process: DNA replication
FT                   initiation (GO:0006270), Biological Process: regulation of
FT                   DNA replication (GO:0006275)). Contains AAA ATPase
FT                   (Interpro|IPR003593, Molecular Function: nucleotide binding
FT                   (GO:0000166))"
FT                   /db_xref="GOA:Q7ARK4"
FT                   /db_xref="InterPro:IPR003593"
FT                   /db_xref="UniProtKB/TrEMBL:Q7ARK4"
FT                   /protein_id="AAS58759.1"
FT                   /translation="MMMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLE
FT                   HLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNE
FT                   NIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGV
FT                   MAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALT
FT                   SAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
FT   gene            2925..3119
FT                   /gene="rop"
FT                   /locus_tag="YP_pPCP03"
FT                   /old_locus_tag="pPCP03"
FT                   /note="synonym: rom"
FT   CDS             2925..3119
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="rop"
FT                   /locus_tag="YP_pPCP03"
FT                   /old_locus_tag="pPCP03"
FT                   /product="putative replication regulatory protein"
FT                   /note="Best Blastp hit =gi|16082682|ref|NP_395229.1|
FT                   (NC_003132) putative replication regulatory protein
FT                   [Yersinia pestis], gi|5763813|emb|CAB531 66.1| (AL109969)
FT                   putative replication regulatory protein [Yersinia pestis];
FT                   similar to gb|AAK91579.1| (AY048853), RNAI modulator
FT                   protein Rom [Salmonella choleraesuis], Contains Regulatory
FT                   protein Rop (Interpro|IPR000769)"
FT                   /db_xref="HSSP:1ROP"
FT                   /db_xref="InterPro:IPR000769"
FT                   /db_xref="UniProtKB/TrEMBL:Q9S1E1"
FT                   /protein_id="AAS58760.1"
FT                   /translation="MNKQQQTALNMARFIRSQSLILLEKLDALDADEQAAMCERLHELA
FT                   EELQNSIQARFEAESETGT"
FT   gene            3486..3857
FT                   /locus_tag="YP_pPCP04"
FT                   /old_locus_tag="pPCP04"
FT   CDS             3486..3857
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="YP_pPCP04"
FT                   /old_locus_tag="pPCP04"
FT                   /product="conserved hypothetical protein"
FT                   /note="Best Blastp hit = gi|321919|pir||JQ1541 hypothetical
FT                   16.9K protein - Salmonella typhi murium plasmid NTP16."
FT                   /db_xref="UniProtKB/TrEMBL:Q74YE8"
FT                   /protein_id="AAS58761.1"
FT                   /translation="MSKKRRPQKRPRRRRFFHRLRPPDEHHKNRRSSQRWRNPTGLKDT
FT                   RRFPPEAPSCALLFRPCRLPDTSPPFSLREAWRFLIAHAVGISVRCRSFAPSWAVCTNP
FT                   PFSPTTAPYPVTIVLSPTR"
FT   misc_feature    3498..3626
FT                   /locus_tag="YP_pPCP04"
FT                   /old_locus_tag="pPCP04"
FT                   /note="ProfileScan match to entry PS50323 ARG_RICH, E-value
FT                   8.981"
FT   gene            4343..4780
FT                   /gene="pim"
FT                   /locus_tag="YP_pPCP05"
FT                   /old_locus_tag="pPCP05"
FT   CDS             4343..4780
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="pim"
FT                   /locus_tag="YP_pPCP05"
FT                   /old_locus_tag="pPCP05"
FT                   /product="pesticin immunity protein"
FT                   /note="similar to many previously sequenced pesticin
FT                   immunity protein entries of Yersinia pestis plasmid pPCP,
FT                   e.g. gi| 16082683|,ref|NP_395230.1| (NC_003132) ,
FT                   gi|1200166|emb|CAA90861.1| (Z54145 ) , gi|1488655|
FT                   emb|CAA63439.1| (X92856) , gi|2996219|gb|AAC62543.1|
FT                   (AF053945) , and gi|5763814|emb|CAB531 67.1| (AL109969)"
FT                   /db_xref="UniProtKB/TrEMBL:Q74YE7"
FT                   /protein_id="AAS58762.1"
FT                   /translation="MGGGMISKLFCLALIFLSSSGLAEKNTYTAKDILQNLELNTFGNS
FT                   LSHGIYGKQTTFKQTEFTNIKSNTKKHIALINKDNSWMISLKILGIKRDEYTVCFEDFS
FT                   LIRPPTYVAIHPLLIKKVKSGNFIVVKEIKKSIPGCTVYYH"
FT   gene            complement(4815..5888)
FT                   /gene="pst"
FT                   /locus_tag="YP_pPCP06"
FT                   /old_locus_tag="pPCP06"
FT   CDS             complement(4815..5888)
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="pst"
FT                   /locus_tag="YP_pPCP06"
FT                   /old_locus_tag="pPCP06"
FT                   /product="pesticin"
FT                   /note="Best Blastp hit =|16082684|ref|NP_395231.1|
FT                   (NC_003132) pesticin [Yersinia pestis],
FT                   gi|984824|gb|AAA75369.1| (U31974) pesticin [Yersinia
FT                   pestis], gi|1488654|emb|CAA63438.1| (X92856) pesticin
FT                   [Yersinia pestis], gi|2996220|gb|AAC62544.1| (AF053945)
FT                   pesticin [Yersinia pestis], gi|5763815|emb|CAB53168.1|
FT                   (AL1099 69) pesticin [Yersinia pestis]"
FT                   /db_xref="UniProtKB/TrEMBL:Q57159"
FT                   /protein_id="AAS58763.1"
FT                   /translation="MSDTMVVNGSGGVPAFLFSGSTLSSYRPNFEANSITIALPHYVDL
FT                   PGRSNFKLMYIMGFPIDTEMEKDSEYSNKIRQESKISKTEGTVSYEQKITVETGQEKDG
FT                   VKVYRVMVLEGTIAESIEHLDKKENEDILNNNRNRIVLADNTVINFDNISQLKEFLRRS
FT                   VNIVDHDIFSSNGFEGFNPTSHFPSNPSSDYFNSTGVTFGSGVDLGQRSKQDLLNDGVP
FT                   QYIADRLDGYYMLRGKEAYDKVRTAPLTLSDNEAHLLSNIYIDKFSHKIEGLFNDANIG
FT                   LRFSDLPLRTRTALVSIGYQKGFKLSRTAPTVWNKVIAKDWNGLVNAFNNIVDGMSDRR
FT                   KREGALVQKDIDSGLLK"
FT   variation       5910..5911
FT                   /replace=""
FT                   /note="compared to AF053945"
FT   variation       5933^5934
FT                   /replace="a"
FT                   /note="compared to AL109969"
FT   variation       5933^5934
FT                   /replace="aa"
FT                   /note="compared to AF053945"
FT   variation       5948
FT                   /replace="c"
FT                   /note="compared to AL109969"
FT   gene            6005..6421
FT                   /locus_tag="YP_pPCP07"
FT                   /old_locus_tag="pPCP07"
FT   CDS             6005..6421
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="YP_pPCP07"
FT                   /old_locus_tag="pPCP07"
FT                   /product="conserved hypothetical proteins"
FT                   /note="Best Blastp hit = gi|16082685|ref|NP_395232.1|
FT                   (NC_003132) hypothetical protein [Yersinia pestis],
FT                   gi|5763816|emb|CAB53169.1| (AL109969) hypothetical protein
FT                   [Yersinia pestis]"
FT                   /db_xref="UniProtKB/TrEMBL:Q9S1E0"
FT                   /protein_id="AAS58764.1"
FT                   /translation="MKFHFCDLNHSYKNQEGKIRSRKTAPGNIRKKQKGDNVSKTKSGR
FT                   HRLSKTDKRLLAALVVAGYEERTARDLIQKHVYTLTQADLRHLVSEISNGVGQSQAYDA
FT                   IYQARRIRLARKYLSGKKPEGVEPREGQEREDLP"
FT   variation       6525
FT                   /replace="c"
FT                   /note="compared to AF053945 and AL109969"
FT   gene            6664..7602
FT                   /gene="pla"
FT                   /locus_tag="YP_pPCP08"
FT                   /old_locus_tag="pPCP08"
FT   CDS             6664..7602
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /gene="pla"
FT                   /locus_tag="YP_pPCP08"
FT                   /old_locus_tag="pPCP08"
FT                   /product="plasminogen activator"
FT                   /note="similar to many previosly sequenced
FT                   coagulase/fibrinolysin precursor (plasminogen activator )
FT                   of Yersinia pestis plasmid pPCP from difference strains,
FT                   e.g. gi|16082686|ref|NP_395233.1| , gi|116897|sp|P17811|,
FT                   gi|96995|pir||A30916 , gi|48630|emb|CAA33235.1| ( X15136),
FT                   gi|2996221|gb|AAC62545.1| (AF053945),and
FT                   gi|5763817|emb|CAB53170.1| (AL109969 ); The 279th aa is T
FT                   (Thr) in reference entries, and in this sequence it is
FT                   I(Ile). Contains Omptin serine protease
FT                   (Interpro|IPR000036, Biological Process: proteolysis and
FT                   peptidolysis (GO:0006508), Molecular Function: serine-type
FT                   peptidase (GO:0008236), Cellular Component: external outer
FT                   membrane (sensu Gram-negative Bacteria) (GO:0009279))"
FT                   /db_xref="GOA:P17811"
FT                   /db_xref="HSSP:1I78"
FT                   /db_xref="InterPro:IPR001702"
FT                   /db_xref="UniProtKB/Swiss-Prot:P17811"
FT                   /protein_id="AAS58765.1"
FT                   /translation="MKKSSIVATIITILSGSANAASSQLIPNISPDSFTVAASTGMLSG
FT                   KSHEMLYDAETGRKISQLDWKIKNVAILKGDISWDPYSFLTLNARGWTSLASGSGNMDD
FT                   YDWMNENQSEWTDHSSHPATNVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFSWTA
FT                   TGGSYSYNNGAYTGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVRA
FT                   HDNDEHYMRDLTFREKTSGSRYYGTVINAGYYVTPNAKVFAEFTYSKYDEGKGGTQIID
FT                   KNSGDSVSIGGDAAGISNKNYTVTAGLQYRF"
FT   gene            complement(7789..8088)
FT                   /locus_tag="YP_pPCP09"
FT                   /old_locus_tag="pPCP09"
FT   CDS             complement(7789..8088)
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="YP_pPCP09"
FT                   /old_locus_tag="pPCP09"
FT                   /product="putative transcriptional regulator"
FT                   /note="Best Blastp hit = gi|16082687|ref|NP_395234.1|
FT                   (NC_003132) putative transcriptional regulator [Yersinia
FT                   pestis], gi|5763818|emb|CAB53171.1| (AL109969) putative
FT                   transcriptional regulator [Yersinia pestis]."
FT                   /db_xref="GOA:Q9S1D9"
FT                   /db_xref="InterPro:IPR001387"
FT                   /db_xref="UniProtKB/TrEMBL:Q9S1D9"
FT                   /protein_id="AAS58766.1"
FT                   /translation="MRTLDEVIASRSPESQTRIKEMADEMILEVGLQMMREELQLSQKQ
FT                   VAEAMGISQPAVTKLEQRGNDLKLATLKRYVEAMGGKLSLDVELPTGRRVAFHV"
FT   gene            complement(8088..8360)
FT                   /locus_tag="YP_pPCP10"
FT                   /old_locus_tag="pPCP10"
FT   CDS             complement(8088..8360)
FT                   /codon_start=1
FT                   /transl_table=11
FT                   /locus_tag="YP_pPCP10"
FT                   /old_locus_tag="pPCP10"
FT                   /product="conserved hypothetical protein"
FT                   /note="Best Blastp hit = gi|16082688|ref|NP_395235.1|
FT                   (NC_003132) hypothetical protein [ Yersinia pestis],
FT                   gi|5763819|emb|CAB53172.1| (AL109969) hypothetical protein
FT                   [Yersinia pestis]"
FT                   /db_xref="UniProtKB/TrEMBL:Q74YE3"
FT                   /protein_id="AAS58767.1"
FT                   /translation="MADLKKLQVYGPELPRPYADTVKGSRYKNMKELRVQFSGRPIRAF
FT                   YAFDPIRRAIVLCAGDKSNDKRFYEKLVRIAEDEFTAHLNTLESK"
FT   variation       8529^8530
FT                   /replace="tt"
FT                   /note="compared to AL109969"
XX
SQ   Sequence 9609 BP; 2792 A; 2250 C; 2099 G; 2468 T; 0 other;
     tgtaacgaac ggtgcaatag tgatccacac ccaacgcctg aaatcagatc cagggggtaa        60
     tctgctctcc tgattcagga gagtttatgg tcacttttga gacagttatg gaaattaaaa       120
     tcctgcacaa gcagggaatg agtagccggg cgattgccag agaactgggg atctcccgca       180
     ataccgttaa acgttatttg caggcaaaat ctgagccgcc aaaatatacg ccgcgacctg       240
     ctgttgcttc actcctggat gaataccggg attatattcg tcaacgcatc gccgatgctc       300
     atccttacaa aatcccggca acggtaatcg ctcgcgagat cagagaccag ggatatcgtg       360
     gcggaatgac cattctcagg gcattcattc gttctctctc ggttcctcag gagcaggagc       420
     ctgccgttcg gttcgaaact gaacccggac gacagatgca ggttgactgg ggcactatgc       480
     gtaatggtcg ctcaccgctt cacgtgttcg ttgctgttct cggatacagc cgaatgctgt       540
     acatcgaatt cactgacaat atgcgttatg acacgctgga gacctgccat cgtaatgcgt       600
     tccgcttctt tggtggtgtg ccgcgcgaag tgttgtatga caatatgaaa actgtggttc       660
     tgcaacgtga cgcatatcag accggtcagc accggttcca tccttcgctg tggcagttcg       720
     gcaaggagat gggcttctct ccccgactgt gtcgcccctt cagggcacag actaaaggta       780
     aggtggaacg gatggtgcag tacacccgta acagttttta catcccacta atgactcgcc       840
     tgcgcccgat ggggatcact gtcgatgttg aaacagccaa ccgccacggt ctgcgctggc       900
     tgcacgatgt cgctaaccaa cgaaagcatg aaacaatcca ggcccgtccc tgcgatcgct       960
     ggctcgaaga gcagcagtcc atgctggcac tgcctccgga gaaaaaagag tatgacgtgc      1020
     atcttgatga aaatctggtg aacttcgaca aacaccccct gcatcatcca ctctccatct      1080
     acgactcatt ctgcagagga gtggcgtgat gatggaactg caacatcaac gactgatggc      1140
     gctcgccggg cagttgcaac tggaaagcct tataagcgca gcgcctgcgc tgtcacaaca      1200
     ggcagtagac caggaatgga gttatatgga cttcctggag catctgcttc atgaagaaaa      1260
     actggcacgt catcaacgta aacaggcgat gtatacccga atggcagcct tcccggcggt      1320
     gaaaacgttc gaagagtatg acttcacatt cgccaccgga gcaccgcaga agcaactcca      1380
     gtcgttacgc tcactcagct tcatagaacg taatgaaaat atcgtattac tggggccatc      1440
     aggtgtgggg aaaacccatc tggcaatagc gatgggctat gaagcagtcc gtgcaggtat      1500
     caaagttcgc ttcacaacag cagcagatct gttacttcag ttatctacgg cacaacgtca      1560
     gggccgttat aaaacgacgc ttcagcgtgg agtaatggcc ccccgcctgc tcatcattga      1620
     tgaaataggc tatctgccgt tcagtcagga agaagcaaag ctgttcttcc aggtcatcgc      1680
     taaacgttac gaaaagagcg caatgatcct gacatccaat ctgccgttcg ggcagtggga      1740
     tcaaacgttc gccggtgatg cagcactgac ctcagcgatg ctggaccgta tcttacacca      1800
     ctcacatgtc gttcaaatca aaggagaaag ctatcgactc agacagaaac gaaaggccgg      1860
     ggttatagca gaagctaatc ctgagtaaaa cggtggatca atattgggcc gttggtggag      1920
     atataagtgg atcacttttc atccgtcgtt gacaccctga tgaattcacg tgttcacgcc      1980
     tgaataacaa gaatgccgga gatacgcagt catatttttt acacaattct ctaatcccga      2040
     caaggtcgta ggtcgttata ggaaaattct tagcaccatt ccggaacaat cagaacagca      2100
     ggccatgaac gactgacaac attacgaata taaaaaacgc acccgggcca gacattcccc      2160
     ctactgatta aaccagccgg acttgtccac ggaacggtct ttttaaaccg acacacagtc      2220
     tgagtacaga tacatgtcac gatgatgcag gattagcgga agagtgtgag cacgtttccg      2280
     ggaactgtgg tgaaccatag ctcaatattc gagtgagggc ataccggaaa cgcgctcaga      2340
     ttcgttgtaa cgcgattttc cgtaccgggc aattttttca gttgtttttt cgtttcatgt      2400
     cgtcagaaac gttctgagcg cgtttccggc atctgatgct acgcaaacca tccccatggt      2460
     cagttgacag ccggaaacac gcgggtgtcg ttttagcgta tcgacgggac ggcgtcgaga      2520
     agcacaaaaa acagatgttg tactcagtca gttgttttac agacagcact gcggcagatt      2580
     gaaaaagtac cgtactttca ggaatgtcca gaaaccatgt gtcagacttc gttctccccc      2640
     ttccgggtga atttttttgt catccgttca ggaatctctt tataacgatt actccatttc      2700
     aggatttttt atgtggcgtt tactacaggc aggatattca aaggcaaaaa aatcccccgg      2760
     aacaggcgga acccggacag ggggagaacg aatcgctaaa taattttcgt agttgtattt      2820
     cccatcgttg ctactgcaac gggatgaatt tgccgcagtt tatcctgtaa aacaatcctg      2880
     atttactcac actccacata tcactgacgg agcacaacgg aatagtgaac aaacaacaac      2940
     aaactgcgct gaatatggcg cgatttatca gaagccagag cctgatactg cttgaaaaac      3000
     tggatgctct ggatgccgac gagcaggcgg ccatgtgtga acgactgcac gaactcgcgg      3060
     aagaactcca gaacagcatc caggctcgct ttgaagccga aagtgaaaca ggaacataac      3120
     gaagctcccg gagacggtca cagcttgtct gtgaacggat gccgggagca gacaagcccg      3180
     tcagggcgcg tcagcgggtt ttagcgggtg tcggggcgca gccatgaccc agtcacgtag      3240
     cgatagcgga gtgtatactg gcttagtcat gcggcatcag tgcggattgt atgaaaagtg      3300
     caccatgtac ggtgtgaaat gccgcacaga tgcgtaagga gaacatgcag atgccgatgc      3360
     tcttccgctt cctcgctcac tgactcgctg cgctcggtcg ttcggctgcg gcgagcggtg      3420
     tctgctcact caaaagcggt gatactgtta tccacacaat caggggataa cgccggaaag      3480
     aacatgtgag caaaaaacga agaccccaga aaaggccgcg ccggaggcgc tttttccata      3540
     ggctccgccc ccctgacgag catcacaaaa atcgacgctc aagtcagagg tggcgaaacc      3600
     cgacaggact taaagatacc aggcgtttcc ccccggaagc tccctcgtgc gctctcctgt      3660
     tccgaccctg ccgcttaccg gatacctctc cgcctttctc ccttcgggaa gcgtggcgct      3720
     ttctcatagc tcacgctgtt ggtatctcag ttcggtgtag gtcgttcgct ccaagctggg      3780
     ctgtgtgcac gaaccccccg ttcagcccga ccactgcgcc ttatccggta actatcgtct      3840
     tgagtccaac ccggtaagac acgactttac gccactggca gcagccattg gtaactgaaa      3900
     agtggattta gatacgcaga actcttgaag ttgaagcctt atcgcggcta cactgaaagg      3960
     acagcatttg gtatctgtgc tccacttaag ccagctacca caggttagaa agcctgagaa      4020
     acttctaacc ttcgaaagaa cccacgcctg agaacgtggg ttttttcgtt tacaggcagc      4080
     agattacgcg cagaaaaaaa ggatctcaag aagatccttt gatcttttct actgaattgc      4140
     gctcccgatc agttcagcag aagattatga tggggttcta tgggtattgc tgcggtaaca      4200
     cccatgttac ttgaggttgt atgtagtctg tgtagaatta tacacataag gcttaaactg      4260
     ctcttttttt tcaatatgca attggaagtt cattgactac ataaatagat tattccaaat      4320
     aatttattta tgtaagaaca ggatgggagg gggaatgatc tcaaagttat tttgcttggc      4380
     tctcatattt ttatcatcaa gtggccttgc agaaaaaaac acatatacag caaaagacat      4440
     cttgcaaaac ctagaattaa atacctttgg caattcattg tctcatggca tctatgggaa      4500
     acagacaacc ttcaagcaaa ccgagtttac aaatattaaa agcaacacca aaaaacacat      4560
     tgcacttatc aataaagaca actcatggat gatatcatta aaaatactag gaattaagag      4620
     agatgagtat actgtctgtt ttgaagattt ctctctaata agaccgccaa catatgtagc      4680
     catacatcct ctacttataa aaaaagtaaa atctggaaac tttatagtag tgaaagaaat      4740
     aaagaaatct atccctggtt gcactgtata ttatcattaa tagcaagccc ctcattatta      4800
     tgaggggctc atggttattt taacaatcca ctatcgatat ctttttgcac cagagcgccc      4860
     tctcgtttac gtctgtcaga cattccatca acaatattat taaaagcatt tacaaggcca      4920
     ttccagtctt ttgcgataac tttattccat actgtgggag cagttctgga taacttaaac      4980
     cctttttgat atccaataga caccagtgct gtacgggttc tcaacggtaa atcgctgaac      5040
     cgaagaccga tattagcgtc attgaaaaga ccttcaatct tatgtgagaa tttatcaata      5100
     taaatattag ataagagatg agcttcatta tcagaaagcg tcagaggtgc tgttctcact      5160
     ttatcataag cctccttccc tcgaagcata taatacccat caagtctatc tgcaatatac      5220
     tgagggacac cgtcattcaa taaatcctgt ttgcttcgct gaccaaggtc aaccccggaa      5280
     ccgaatgtaa caccggtact gttaaaataa tcgctactag gattagacgg aaaatgactt      5340
     gtcggattaa acccttcaaa accattactg gagaaaatat cgtggtcaac aatatttacc      5400
     gaacgacgta aaaattcctt cagttgacta atattgtcaa agttaatgac agtgttgtcc      5460
     gctaggacga tgcgatttcg gttattattc agaatgtctt cgttctcttt cttatcgaga      5520
     tgttcaatag attcggcaat cgttccctca agaaccatga cacggtagac tttcacaccg      5580
     tctttttcct gacctgtttc aacagttatt ttctgttcgt aagacacggt cccttcagtt      5640
     tttgaaattt tactttcctg gcggatctta tttgaatatt cactgtcttt ctccatctcc      5700
     gtatcaatcg gaaaccccat aatgtacatc agtttaaaat tactccggcc aggcagatcc      5760
     acataatgtg gtaatgcaat tgtaatcgaa ttagcttcaa aatttggtct gtaactgctt      5820
     aatgtacttc cggaaaagag aaaagccgga acaccacctg aaccattcac taccattgta      5880
     tctgacataa aaattcctct ttaacacata aaaaaaacaa taagttaaaa aaatactgta      5940
     cataaaagca ctgtttttat gtacagtaat aaaattacgc cgctttattt tctctgtcaa      6000
     taatatgaaa tttcattttt gtgatctgaa tcactcttat aaaaatcagg aagggaagat      6060
     tcgcagcaga aaaacagcac cgggtaacat cagaaaaaaa cagaaaggag ataacgtgag      6120
     caaaacaaaa tctggtcgcc accgactgag caaaacagac aaacgcctgc tggctgcact      6180
     tgtcgttgcc ggatacgaag aacggacagc ccgtgacctc atccagaaac acgtttacac      6240
     actgacacag gccgacctgc gccatctggt cagtgaaatc agtaacggtg tgggacagtc      6300
     acaggcctac gatgcgattt accaggcgag acgcattcgt ctcgcccgta aatacctgag      6360
     cggaaaaaaa ccggaagggg tggaaccccg ggaagggcag gaacgggaag atttaccata      6420
     actcccgtta tcagtaccat cggctcaacg ctcgttgtcg gatctgaaaa attcgctcaa      6480
     aagatcatat ttccctggat attttccacc gtttcttatg tgagaaaagt cacataattc      6540
     tgtcagacga cgagaaaacg gatatcgatt attgtttaat atttttacat tattaaaaat      6600
     gaaattagat aatcagatac aaataatatg ttttcgttca tgcagagaga ttaagggtgt      6660
     ctaatgaaga aaagttctat tgtggcaacc attataacta ttctgtccgg gagtgctaat      6720
     gcagcatcat ctcagttaat accaaatata tcccctgaca gctttacagt tgcagcctcc      6780
     accgggatgc tgagtggaaa gtctcatgaa atgctttatg acgcagaaac aggaagaaag      6840
     atcagccagt tagactggaa gatcaaaaat gtcgctatcc tgaaaggtga tatatcctgg      6900
     gatccatact catttctgac cctgaatgcc agggggtgga cgtctctggc ttccgggtca      6960
     ggtaatatgg atgactacga ctggatgaat gaaaatcaat ctgagtggac agatcactca      7020
     tctcatcctg ctacaaatgt taatcatgcc aatgaatatg acctcaatgt gaaaggctgg      7080
     ttactccagg atgagaatta taaagcaggt ataacagcag gatatcagga aacacgtttc      7140
     agttggacag ctacaggtgg ttcatatagt tataataatg gagcttatac cggaaacttc      7200
     ccgaaaggag tgcgggtaat aggttataac cagcgctttt ctatgccata tattggactt      7260
     gcaggccagt atcgcattaa tgattttgag ttaaatgcat tatttaaatt cagcgactgg      7320
     gttcgggcac atgataatga tgagcactat atgagagatc ttactttccg tgagaagaca      7380
     tccggctcac gttattatgg taccgtaatt aacgctggat attatgtcac acctaatgcc      7440
     aaagtctttg cggaatttac atacagtaaa tatgatgagg gcaaaggagg tactcagatc      7500
     attgataaga atagtggaga ttctgtctct attggcggag atgctgccgg tatttccaat      7560
     aaaaattata ctgtgacggc gggtctgcaa tatcgcttct gaaaaataca gatcatatct      7620
     ctcttttcat cctcccctag cggggaggat gtctgtggaa aggaggttgg tgtttgacca      7680
     accttcagat gtgtgaaaaa tcaccttttt caccataatg acggggcgct cattctgttg      7740
     ttttgccttg acattctcca cgtctttcag ggcatggaga aggtcaaatt agacatggaa      7800
     cgctactctc cttcctgtag gaagctcaac atccaagctt aatttgcctc ccattgcttc      7860
     aacgtaacgc tttaacgtcg ccagctttaa atcatttccg cgctgctcca gctttgttac      7920
     tgctggctgg cttataccca tcgcctcagc aacttgtttt tgtgataact ggagttcttc      7980
     acgcatcatc tgcaagccga cctcaagaat catctcatct gccatttctt taattcgtgt      8040
     ctggctttca ggtgaacgac tggcaatcac ctcatctaat gttctcatta cttgctctcc      8100
     agtgtgttca gatgtgctgt aaattcatcc tcagctatac gcaccagttt ttcataaaac      8160
     cgcttatcat tacttttatc tcctgcacaa agaacgatag cccgacgaat cggatcgaac      8220
     gcataaaagg ctcttatcgg acggccagaa aactgaacgc gaagctcttt catatttttg      8280
     taccgagaac ctttcacggt atcggcatat ggcctgggta actcaggtcc gtaaacctgt      8340
     agctttttca aatcagccaa aaccttttcc tgaagagcgt cttcttgctc atttagccag      8400
     tcgtcaaatc gctggctaaa aagtaccatc cacatgctca accctataac ctgtagctta      8460
     ccccactaac aatataacct acgagttata ttttcaagaa aagctggcta tttaacataa      8520
     cggcaatttg tacgcaccac tgaaatgcgt tcagcgcgat cacggcaaca gacaggcaaa      8580
     aatagcaaca aacctcccga aaaaccgccg cgatcgcgcc tgataaattt taaccttatg      8640
     catatctatg cagccaggcg aatcacgaac gaattgcctg cctgatgtaa ctgaaacggg      8700
     tgttttttcc tgatttggtg ggcgtggaag acggaacatg aacgggaaaa cagaattcat      8760
     gccagatgag cgcgatctgg caattaaggc aaaacacagc aacaaagaca cgccagaatc      8820
     gcgcccggat atgttttaac gcgattttca gactcagaca aattcagcag aatgctactc      8880
     cattcaccgg gctgatggtg aatacatgcg tatccaggat gagtacattt ctggctctgc      8940
     cacagctctg tctgttggca gctttcgcct gtccggaaac ctgcttaaaa cgctcccgaa      9000
     aggcctctga accagaaagc aacaaaacac aggccattaa gtaaatcgcg ttaaaacacg      9060
     tctgatggat tgctgcaaaa aaaagtccct aatggagcag ggactgttaa acccagtgaa      9120
     tagcgtctaa attaaagtaa gaatacgacc aggtactctt cagaaaagag attaatccac      9180
     cgcacagaat aatcaacagt aaaaacaaac aaccctgatt ttttattttt ctttttttcg      9240
     ataaaaacaa aattaaagaa ataattaatc agaacattcc ttaacttcag ggcattgcct      9300
     gtgttccatt ttgtgattag tctgaaactt ccgaaggtgg ataacacccg gtattttttt      9360
     gctcacataa agcccctcct tcaggcagag gggctttttc tttgccacca cataaaaaag      9420
     gccctcacag gaggtgttct gtgagggcgt atgataagga ctgaatcgat ggttaatatg      9480
     tctagtcctg acttttgcat ctccgaatat aaaaccctgt ttaacggcat gcaaaaccaa      9540
     aaaataaaaa tgtgacatcg caatgccaga taatattgac gcatgaggga atgcgtaccc      9600
     cgacccctg                                                              9609
//
