<?xml version='1.0' encoding='UTF-8'?>
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<entry dataset="TrEMBL" created="2013-07-24" modified="2016-09-07" version="15">
<accession>R5HY77</accession>
<name>R5HY77_9BACT</name>
<protein>
<recommendedName>
<fullName evidence="1">Elongation factor Ts</fullName>
<shortName evidence="1">EF-Ts</shortName>
</recommendedName>
</protein>
<gene>
<name type="primary" evidence="1">tsf</name>
<name type="ORF" evidence="3">BN796_01519</name>
</gene>
<organism evidence="3 4">
<name type="scientific">Alistipes sp. CAG:831</name>
<dbReference type="NCBI Taxonomy" id="1262698"/>
<lineage>
<taxon>Bacteria</taxon>
<taxon>Bacteroidetes</taxon>
<taxon>Bacteroidia</taxon>
<taxon>Bacteroidales</taxon>
<taxon>Rikenellaceae</taxon>
<taxon>Alistipes</taxon>
<taxon>environmental samples</taxon>
</lineage>
</organism>
<reference key="1" evidence="3 4">
<citation type="submission" date="2012-11" db="EMBL/GenBank/DDBJ databases">
<title>Dependencies among metagenomic species, viruses, plasmids and units of genetic variation.</title>
<authorList>
<person name="Nielsen H.B."/>
<person name="Almeida M."/>
<person name="Juncker A.S."/>
<person name="Rasmussen S."/>
<person name="Li J."/>
<person name="Sunagawa S."/>
<person name="Plichta D."/>
<person name="Gautier L."/>
<person name="Le Chatelier E."/>
<person name="Peletier E."/>
<person name="Bonde I."/>
<person name="Nielsen T."/>
<person name="Manichanh C."/>
<person name="Arumugam M."/>
<person name="Batto J."/>
<person name="Santos M.B.Q.D."/>
<person name="Blom N."/>
<person name="Borruel N."/>
<person name="Burgdorf K.S."/>
<person name="Boumezbeur F."/>
<person name="Casellas F."/>
<person name="Dore J."/>
<person name="Guarner F."/>
<person name="Hansen T."/>
<person name="Hildebrand F."/>
<person name="Kaas R.S."/>
<person name="Kennedy S."/>
<person name="Kristiansen K."/>
<person name="Kultima J.R."/>
<person name="Leonard P."/>
<person name="Levenez F."/>
<person name="Lund O."/>
<person name="Moumen B."/>
<person name="Le Paslier D."/>
<person name="Pons N."/>
<person name="Pedersen O."/>
<person name="Prifti E."/>
<person name="Qin J."/>
<person name="Raes J."/>
<person name="Tap J."/>
<person name="Tims S."/>
<person name="Ussery D.W."/>
<person name="Yamada T."/>
<person name="MetaHit consortium"/>
<person name="Renault P."/>
<person name="Sicheritz-Ponten T."/>
<person name="Bork P."/>
<person name="Wang J."/>
<person name="Brunak S."/>
<person name="Ehrlich S.D."/>
</authorList>
</citation>
<scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
<source>
<strain evidence="4">MGS:831</strain>
</source>
</reference>
<comment type="function">
<text evidence="1">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
</comment>
<comment type="subcellular location">
<subcellularLocation>
<location evidence="1">Cytoplasm</location>
</subcellularLocation>
</comment>
<comment type="similarity">
<text evidence="1">Belongs to the EF-Ts family.</text>
</comment>
<comment type="caution">
<text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
</comment>
<dbReference type="EMBL" id="CAYB010000029">
<property type="protein sequence ID" value="CCY34813.1"/>
<property type="molecule type" value="Genomic_DNA"/>
</dbReference>
<dbReference type="Proteomes" id="UP000018094">
<property type="component" value="Unassembled WGS sequence"/>
</dbReference>
<dbReference type="GO" id="GO:0005737">
<property type="term" value="C:cytoplasm"/>
<property type="evidence" value="ECO:0000501"/>
<property type="project" value="UniProtKB-SubCell"/>
</dbReference>
<dbReference type="GO" id="GO:0003746">
<property type="term" value="F:translation elongation factor activity"/>
<property type="evidence" value="ECO:0000501"/>
<property type="project" value="UniProtKB-HAMAP"/>
</dbReference>
<dbReference type="Gene3D" id="3.30.479.20">
<property type="match status" value="3"/>
</dbReference>
<dbReference type="HAMAP" id="MF_00050">
<property type="entry name" value="EF_Ts"/>
<property type="match status" value="1"/>
</dbReference>
<dbReference type="InterPro" id="IPR001816">
<property type="entry name" value="Transl_elong_EFTs/EF1B"/>
</dbReference>
<dbReference type="InterPro" id="IPR014039">
<property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
</dbReference>
<dbReference type="InterPro" id="IPR018101">
<property type="entry name" value="Transl_elong_Ts_CS"/>
</dbReference>
<dbReference type="InterPro" id="IPR009060">
<property type="entry name" value="UBA-like"/>
</dbReference>
<dbReference type="PANTHER" id="PTHR11741">
<property type="entry name" value="PTHR11741"/>
<property type="match status" value="2"/>
</dbReference>
<dbReference type="Pfam" id="PF00889">
<property type="entry name" value="EF_TS"/>
<property type="match status" value="1"/>
</dbReference>
<dbReference type="SUPFAM" id="SSF46934">
<property type="entry name" value="SSF46934"/>
<property type="match status" value="1"/>
</dbReference>
<dbReference type="SUPFAM" id="SSF54713">
<property type="entry name" value="SSF54713"/>
<property type="match status" value="4"/>
</dbReference>
<dbReference type="TIGRFAMs" id="TIGR00116">
<property type="entry name" value="tsf"/>
<property type="match status" value="1"/>
</dbReference>
<dbReference type="PROSITE" id="PS01126">
<property type="entry name" value="EF_TS_1"/>
<property type="match status" value="1"/>
</dbReference>
<proteinExistence type="inferred from homology"/>
<keyword id="KW-0181" evidence="4">Complete proteome</keyword>
<keyword id="KW-0963" evidence="1">Cytoplasm</keyword>
<keyword id="KW-0251" evidence="1 3">Elongation factor</keyword>
<keyword id="KW-0648" evidence="1 3">Protein biosynthesis</keyword>
<keyword id="KW-1185" evidence="4">Reference proteome</keyword>
<feature type="domain" description="EF_TS" evidence="2">
<location>
<begin position="71"/>
<end position="328"/>
</location>
</feature>
<feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="1">
<location>
<begin position="79"/>
<end position="82"/>
</location>
</feature>
<evidence key="1" type="ECO:0000256">
<source>
<dbReference type="HAMAP-Rule" id="MF_00050"/>
</source>
</evidence>
<evidence key="2" type="ECO:0000259">
<source>
<dbReference type="Pfam" id="PF00889"/>
</source>
</evidence>
<evidence key="3" type="ECO:0000313">
<source>
<dbReference type="EMBL" id="CCY34813.1"/>
</source>
</evidence>
<evidence key="4" type="ECO:0000313">
<source>
<dbReference type="Proteomes" id="UP000018094"/>
</source>
</evidence>
<sequence length="331" mass="35648" checksum="ECF3BC99C5D8BFF1" modified="2013-07-24" version="1">
MEIKAIDVQKLRKMTGAGMMDCKKALIEANGDYERAKEIIREKGKLVAAKRADRETSEGA
VVAKVDGSKGILLCLGCETDFVAKNEEFQALANAIADAAIKALPADMEALKACTIADGRT
VEAAITEQIGKTGEKHSLVAYEKVEAPYIISYIHTINGKLGAIVGFNKEVPVDLAKGVAM
QVASMNPVAVNKEAVPQNVIDEELKVAVEKTKEELVKKAVDAALSKAGINPAHVDSEDHI
QSNTAKGWLTPEQADQAREIIRTVSAEKAANLQEAMVNNIANGRLNKFFKENTLEEQEYQ
MGDGKTSVKAAIAAVDKDAKVTVFKRISLVD
</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
</copyright>
</uniprot>