********************************************************************************
MAST - Motif Alignment and Search Tool
********************************************************************************
	MAST version 5.0.1 (Release date: Wed Aug 22 15:26:53 2018 -0700)

	For further information on how to interpret these results please access http://meme-suite.org.
	To get a copy of the MAST software please access http://meme-suite.org.
********************************************************************************


********************************************************************************
REFERENCE
********************************************************************************
	If you use this program in your research, please cite:

	Timothy L. Bailey and Michael Gribskov,
	"Combining evidence using p-values: application to sequence homology
	searches", Bioinformatics, 14(48-54), 1998.
********************************************************************************


********************************************************************************
DATABASE AND MOTIFS
********************************************************************************
	DATABASE Klf1-200.fa (nucleotide)
	Last updated on Fri Jan 19 17:27:01 2018
	Database contains 200 sequences, 100000 residues

	Scores for positive and reverse complement strands are combined.

	MOTIFS meme.Klf1-200.cd.oops.xml (nucleotide)
	MOTIF ID                             ALT ID WIDTH BEST POSSIBLE MATCH
	----- ------------------------------ ------ ----- -------------------
	    1 RGMWGGGTGTGGCYNSNKNN           MEME-1    20 AGCTGGGTGTGGCCGGGGGT
	    2 TNVHHBCTBNYYBNHHYYYCTTVTCTCTGB MEME-2    30 TTGCTCCTCTCTTTTACCTCTTATCTCTGG

	PAIRWISE MOTIF CORRELATIONS:
	MOTIF     1
	----- -----
	   2   0.21
	No overly similar pairs (correlation > 0.60) found.

	Random model letter frequencies (from non-redundant database):
	A 0.274 C 0.225 G 0.225 T 0.274 
********************************************************************************


********************************************************************************
SECTION I: HIGH-SCORING SEQUENCES
********************************************************************************
	- Each of the following 113 sequences has E-value less than 10.
	- The E-value of a sequence is the expected number of sequences
	  in a random database of the same size that would match the motifs as
	  well as the sequence does and is equal to the combined p-value of the
	  sequence times the number of sequences in the database.
	- The combined p-value of a sequence measures the strength of the
	  match of the sequence to all the motifs and is calculated by
	    o finding the score of the single best match of each motif
	      to the sequence (best matches may overlap),
	    o calculating the sequence p-value of each score,
	    o forming the product of the p-values,
	    o taking the p-value of the product.
	- The sequence p-value of a score is defined as the
	  probability of a random sequence of the same length containing
	  some match with as good or better a score.
	- The score for the match of a position in a sequence to a motif
	  is computed by by summing the appropriate entry from each column of
	  the position-dependent scoring matrix that represents the motif.
	- Sequences shorter than one or more of the motifs are skipped.
	- The table is sorted by increasing E-value.
********************************************************************************

SEQUENCE NAME                      DESCRIPTION                   E-VALUE  LENGTH
-------------                      -----------                   -------- ------
chr3:104843905-104844405                                          0.00014    500
chr12:114390660-114391160                                         0.00048    500
chr12:27135944-27136444                                           0.00085    500
chr10:59256089-59256589                                            0.0069    500
chr4:135733850-135734350                                           0.0077    500
chr1:137838164-137838664                                           0.0091    500
chr17:47735006-47735506                                             0.012    500
chr6:72223026-72223526                                              0.014    500
chr13:3866266-3866766                                               0.014    500
chr1:133343883-133344383                                             0.02    500
chr11:117187372-117187872                                            0.02    500
chr13:76003199-76003699                                             0.022    500
chr5:65202593-65203093                                              0.024    500
chr14:79702844-79703344                                             0.026    500
chr12:112796794-112797294                                           0.026    500
chr13:112863645-112864145                                           0.032    500
chr7:111007530-111008030                                            0.037    500
chr1:43307690-43308190                                              0.038    500
chr14:47973722-47974222                                              0.04    500
chr9:120025371-120025871                                            0.046    500
chr7:105490727-105491227                                            0.049    500
chr5:37127175-37127675                                              0.058    500
chr5:45951565-45952065                                              0.058    500
chr7:91033422-91033922                                              0.061    500
chr4:154285745-154286245                                            0.064    500
chr13:100518008-100518508                                           0.071    500
chr1:36977019-36977519                                              0.074    500
chr7:151917814-151918314                                            0.079    500
chr7:110976195-110976695                                            0.082    500
chr15:58719281-58719781                                             0.095    500
chr11:57590460-57590960                                               0.1    500
chr8:83025150-83025650                                               0.11    500
chr13:54345922-54346422                                              0.12    500
chr12:82044358-82044858                                              0.12    500
chr11:105013714-105014214                                            0.13    500
chr10:93585404-93585904                                              0.14    500
chr7:19832207-19832707                                               0.16    500
chr8:97323995-97324495                                               0.21    500
chr10:126642277-126642777                                            0.23    500
chr1:156887119-156887619                                             0.24    500
chr15:81700367-81700867                                              0.25    500
chr6:121187425-121187925                                             0.25    500
chr4:43977111-43977611                                               0.31    500
chr11:102236405-102236905                                            0.31    500
chr17:5112057-5112557                                                0.32    500
chr10:110604369-110604869                                            0.33    500
chr1:169314208-169314708                                             0.35    500
chr9:57618594-57619094                                               0.36    500
chr10:128184604-128185104                                            0.38    500
chr4:109112541-109113041                                              0.4    500
chr3:97461668-97462168                                               0.46    500
chr9:102674395-102674895                                             0.48    500
chr17:24289205-24289705                                               0.5    500
chr17:28960252-28960752                                              0.53    500
chr2:73323093-73323593                                               0.61    500
chr11:32150818-32151318                                              0.63    500
chr7:103853792-103854292                                             0.66    500
chr16:49839621-49840121                                              0.71    500
chr6:135115628-135116128                                             0.73    500
chr3:88305500-88306000                                               0.77    500
chr18:57137388-57137888                                              0.78    500
chr5:97380648-97381148                                               0.83    500
chr15:91082416-91082916                                              0.88    500
chr14:61272713-61273213                                              0.91    500
chr5:33616214-33616714                                               0.93    500
chr18:23982470-23982970                                              0.97    500
chr9:24715045-24715545                                               0.99    500
chr10:116195445-116195945                                             1.1    500
chr11:77795184-77795684                                               1.2    500
chr16:32508975-32509475                                               1.3    500
chr18:80416880-80417380                                               1.5    500
chr10:57252236-57252736                                               1.6    500
chr5:34915767-34916267                                                1.7    500
chr9:98389943-98390443                                                1.7    500
chr19:5845899-5846399                                                 1.7    500
chr3:151777796-151778296                                              2.2    500
chr4:76585120-76585620                                                2.2    500
chr7:104332488-104332988                                              2.2    500
chr5:138127197-138127697                                              2.5    500
chr11:60988820-60989320                                               2.5    500
chr8:19984030-19984530                                                2.6    500
chr11:31712262-31712762                                               2.9    500
chr15:41338514-41339014                                                 3    500
chr9:21362671-21363171                                                  3    500
chr18:58822702-58823202                                                 3    500
chr1:173447614-173448114                                              3.4    500
chr6:81915769-81916269                                                3.5    500
chr1:169322898-169323398                                              3.9    500
chr12:70860461-70860961                                               3.9    500
chr9:59598186-59598686                                                3.9    500
chr3:19550495-19550995                                                  4    500
chr7:36132953-36133453                                                  4    500
chr7:38970375-38970875                                                4.1    500
chr15:78243390-78243890                                               4.4    500
chr7:87847381-87847881                                                4.4    500
chr1:33631214-33631714                                                4.4    500
chr4:135407873-135408373                                              4.5    500
chr7:101244829-101245329                                              4.5    500
chr10:60612190-60612690                                               4.7    500
chr19:56465963-56466463                                               4.8    500
chr4:41334759-41335259                                                4.9    500
chr8:92969521-92970021                                                5.2    500
chr6:145703215-145703715                                              5.3    500
chr13:57679178-57679678                                               5.5    500
chr19:45121628-45122128                                               5.6    500
chr15:79757891-79758391                                               5.6    500
chr1:134264178-134264678                                              5.7    500
chr13:81067500-81068000                                               6.4    500
chr11:69714224-69714724                                               6.4    500
chr2:103728071-103728571                                                7    500
chr5:105994747-105995247                                                9    500
chr17:84209565-84210065                                               9.4    500
chr7:16507689-16508189                                                9.6    500

********************************************************************************



********************************************************************************
SECTION II: MOTIF DIAGRAMS
********************************************************************************
	- The ordering and spacing of all non-overlapping motif occurrences
	  are shown for each high-scoring sequence listed in Section I.
	- A motif occurrence is defined as a position in the sequence whose
	  match to the motif has POSITION p-value less than 0.0001.
	- The POSITION p-value of a match is the probability of
	  a single random subsequence of the length of the motif
	  scoring at least as well as the observed match.
	- For each sequence, all motif occurrences are shown unless there
	  are overlaps.  In that case, a motif occurrence is shown only if its
	  p-value is less than the product of the p-values of the other
	  (lower-numbered) motif occurrences that it overlaps.
	- The table also shows the E-value of each sequence.
	- Spacers and motif occurences are indicated by
	   o -d-    `d' residues separate the end of the preceding motif 
		    occurrence and the start of the following motif occurrence
	   o [sn]  occurrence of motif `n' with p-value less than 0.0001.
		    A minus sign indicates that the occurrence is on the
		    reverse complement strand.
********************************************************************************

SEQUENCE NAME                      E-VALUE   MOTIF DIAGRAM
-------------                      --------  -------------
chr3:104843905-104844405            0.00014  115-[-1]-209-[-2]-126
chr12:114390660-114391160           0.00048  3-[+2]-[+2]-3-[+1]-173-[+1]-3-[-2]-188
chr12:27135944-27136444             0.00085  275-[-1]-89-[+2]-4-[+2]-52
chr10:59256089-59256589              0.0069  247-[+2]-17-[-1]-186
chr4:135733850-135734350             0.0077  183-[-1]-263-[+2]-4
chr1:137838164-137838664             0.0091  192-[-2]-1-[+1]-44-[-1]-193
chr17:47735006-47735506               0.012  203-[+2]-15-[+1]-97-[-1]-115
chr6:72223026-72223526                0.014  52-[-2]-7-[+2]-162-[-1]-42-[-1]-137
chr13:3866266-3866766                 0.014  241-[+1]-2-[-1]-217
chr1:133343883-133344383               0.02  190-[+2]-15-[+1]-245
chr11:117187372-117187872              0.02  242-[+1]-46-[-2]-71-[+1]-71
chr13:76003199-76003699               0.022  230-[+2]-15-[+2]-60-[-1]-115
chr5:65202593-65203093                0.024  24-[-2]-36-[+2]-193-[-1]-11-[+1]-10-[+1]-106
chr14:79702844-79703344               0.026  247-[-1]-46-[-2]-157
chr12:112796794-112797294             0.026  232-[+1]-41-[+1]-187
chr13:112863645-112864145             0.032  228-[+1]-20-[-1]-212
chr7:111007530-111008030              0.037  217-[+1]-83-[+2]-150
chr1:43307690-43308190                0.038  164-[-2]-52-[-2]-224
chr14:47973722-47974222                0.04  21-[+1]-181-[+1]-20-[-2]-208
chr9:120025371-120025871              0.046  110-[-2]-58-[+1]-282
chr7:105490727-105491227              0.049  100-[-2]-111-[-1]-239
chr5:37127175-37127675                0.058  234-[-2]-24-[+1]-192
chr5:45951565-45952065                0.058  261-[-1]-219
chr7:91033422-91033922                0.061  465-[-1]-15
chr4:154285745-154286245              0.064  235-[+1]-20-[-2]-195
chr13:100518008-100518508             0.071  226-[-2]-18-[-1]-206
chr1:36977019-36977519                0.074  88-[+1]-187-[+2]-60-[-1]-95
chr7:151917814-151918314              0.079  219-[+1]-80-[+2]-151
chr7:110976195-110976695              0.082  287-[+2]-12-[+1]-151
chr15:58719281-58719781               0.095  212-[-2]-258
chr11:57590460-57590960                 0.1  56-[-1]-271-[-1]-75-[+2]-28
chr8:83025150-83025650                 0.11  219-[+1]-87-[+2]-144
chr13:54345922-54346422                0.12  283-[-2]-161-[+1]-6
chr12:82044358-82044858                0.12  50-[+2]-160-[+1]-39-[+2]-171
chr11:105013714-105014214              0.13  115-[-2]-160-[+1]-26-[-1]-129
chr10:93585404-93585904                0.14  141-[+2]-48-[+1]-261
chr7:19832207-19832707                 0.16  229-[-1]-251
chr8:97323995-97324495                 0.21  177-[-1]-40-[-2]-139-[+1]-74
chr10:126642277-126642777              0.23  252-[-1]-92-[-2]-106
chr1:156887119-156887619               0.24  189-[-2]-78-[-1]-183
chr15:81700367-81700867                0.25  109-[-1]-99-[-1]-252
chr6:121187425-121187925               0.25  29-[+2]-313-[-1]-108
chr4:43977111-43977611                 0.31  60-[+1]-148-[+1]-252
chr11:102236405-102236905              0.31  10-[+2]-145-[-1]-3-[-1]-6-[+2]-60-[+1]-156
chr17:5112057-5112557                  0.32  249-[+1]-231
chr10:110604369-110604869              0.33  232-[+1]-248
chr1:169314208-169314708               0.35  192-[-1]-[-1]-11-[-2]-227
chr9:57618594-57619094                 0.36  125-[+2]-151-[-1]-4-[-1]-150
chr10:128184604-128185104              0.38  30-[-2]-128-[+1]-292
chr4:109112541-109113041                0.4  21-[-1]-13-[+1]-94-[+2]-302
chr3:97461668-97462168                 0.46  18-[+2]-256-[-1]-81-[+1]-21-[+1]-34
chr9:102674395-102674895               0.48  372-[+2]-98
chr17:24289205-24289705                 0.5  262-[-1]-218
chr17:28960252-28960752                0.53  221-[+1]-81-[+1]-158
chr2:73323093-73323593                 0.61  49-[-2]-421
chr11:32150818-32151318                0.63  151-[-1]-27-[-1]-118-[-2]-134
chr7:103853792-103854292               0.66  212-[-2]-42-[+1]-196
chr16:49839621-49840121                0.71  192-[+2]-47-[-1]-17-[+2]-164
chr6:135115628-135116128               0.73  231-[-1]-249
chr3:88305500-88306000                 0.77  229-[+1]-251
chr18:57137388-57137888                0.78  296-[+2]-174
chr5:97380648-97381148                 0.83  188-[-2]-282
chr15:91082416-91082916                0.88  239-[-1]-104-[-1]-73-[+2]-14
chr14:61272713-61273213                0.91  216-[+2]-104-[+1]-130
chr5:33616214-33616714                 0.93  247-[-1]-233
chr18:23982470-23982970                0.97  285-[-1]-195
chr9:24715045-24715545                 0.99  214-[-1]-153-[+1]-93
chr10:116195445-116195945               1.1  400-[+2]-70
chr11:77795184-77795684                 1.2  247-[+1]-42-[-2]-67-[-2]-64
chr16:32508975-32509475                 1.3  213-[+2]-29-[-1]-208
chr18:80416880-80417380                 1.5  239-[-1]-241
chr10:57252236-57252736                 1.6  155-[+1]-158-[+2]-137
chr5:34915767-34916267                  1.7  179-[+2]-29-[-1]-242
chr9:98389943-98390443                  1.7  252-[-1]-228
chr19:5845899-5846399                   1.7  136-[+1]-193-[+1]-131
chr3:151777796-151778296                2.2  30-[-2]-58-[-1]-362
chr4:76585120-76585620                  2.2  329-[+2]-141
chr7:104332488-104332988                2.2  164-[+2]-23-[-1]-222-[+1]-21
chr5:138127197-138127697                2.5  238-[+1]-242
chr11:60988820-60989320                 2.5  115-[+1]-68-[+1]-47-[+1]-210
chr8:19984030-19984530                  2.6  103-[-1]-81-[+2]-266
chr11:31712262-31712762                 2.9  118-[+2]-53-[+2]-269
chr15:41338514-41339014                   3  173-[+2]-75-[+2]-192
chr9:21362671-21363171                    3  105-[+1]-131-[+1]-224
chr18:58822702-58823202                   3  467-[-2]-3
chr1:173447614-173448114                3.4  369-[-1]-111
chr6:81915769-81916269                  3.5  197-[+1]-283
chr1:169322898-169323398                3.9  253-[-1]-227
chr12:70860461-70860961                 3.9  197-[+2]-22-[-1]-231
chr9:59598186-59598686                  3.9  163-[-2]-10-[-1]-277
chr3:19550495-19550995                    4  452-[-2]-18
chr7:36132953-36133453                    4  157-[-1]-323
chr7:38970375-38970875                  4.1  49-[+1]-114-[+1]-297
chr15:78243390-78243890                 4.4  234-[+1]-246
chr7:87847381-87847881                  4.4  99-[+2]-2-[-1]-230-[-1]-99
chr1:33631214-33631714                  4.4  358-[-1]-122
chr4:135407873-135408373                4.5  116-[-1]-64-[+2]-270
chr7:101244829-101245329                4.5  311-[-2]-159
chr10:60612190-60612690                 4.7  215-[+1]-265
chr19:56465963-56466463                 4.8  306-[+1]-36-[+1]-18-[+1]-80
chr4:41334759-41335259                  4.9  204-[+1]-276
chr8:92969521-92970021                  5.2  453-[+2]-17
chr6:145703215-145703715                5.3  154-[-2]-58-[+2]-228
chr13:57679178-57679678                 5.5  217-[-1]-263
chr19:45121628-45122128                 5.6  35-[-2]-435
chr15:79757891-79758391                 5.6  310-[+1]-170
chr1:134264178-134264678                5.7  23-[+2]-447
chr13:81067500-81068000                 6.4  252-[+1]-228
chr11:69714224-69714724                 6.4  145-[+2]-325
chr2:103728071-103728571                  7  369-[+1]-111
chr5:105994747-105995247                  9  93-[+2]-153-[-2]-194
chr17:84209565-84210065                 9.4  64-[-2]-406
chr7:16507689-16508189                  9.6  231-[+2]-239

********************************************************************************



********************************************************************************
SECTION III: ANNOTATED SEQUENCES
********************************************************************************
	- The positions and p-values of the non-overlapping motif occurrences
	  are shown above the actual sequence for each of the high-scoring
	  sequences from Section I.
	- A motif occurrence is defined as a position in the sequence whose
	  match to the motif has POSITION p-value less than 0.0001 as 
	  defined in Section II.
	- For each sequence, the first line specifies the name of the sequence.
	- The second (and possibly more) lines give a description of the 
	  sequence.
	- Following the description line(s) is a line giving the length, 
	  combined p-value, and E-value of the sequence as defined in Section I.
	- The next line reproduces the motif diagram from Section II.
	- The entire sequence is printed on the following lines.
	- Motif occurrences are indicated directly above their positions in the
	  sequence on lines showing
	   o the motif number of the occurrence (a minus sign indicates that
	  the occurrence is on the reverse complement strand),
	   o the position p-value of the occurrence,
	   o the best possible match to the motif (or its reverse complement), and
	   o columns whose match to the motif has a positive score (indicated 
	     by a plus sign).
********************************************************************************


chr3:104843905-104844405
  LENGTH = 500  COMBINED P-VALUE = 7.07e-07  E-VALUE =  0.00014
  DIAGRAM: 115-[-1]-209-[-2]-126

                                             [-1]
                                             9.3e-07
                                             ACCCCCGGCCACACCCAGCT
                                             +++ ++++++++++++ ++
76   TGACAACAATCAGAAGTTCTGGGTATCAAGCCGGGATGCACACGCAGGCCACACCCCTCGCCTTATGCACACACC

                                                 [-2]
                                                 4.6e-08
                                                 CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                                 +++++++ ++++ ++ ++++++++++  ++
301  CTGAAGTGATCCTGTAGGGCAACAGGCATAGCTGTGTTTTCACCACAGAGACAAGGTGGCAAGAAAAGAAAACAC


chr12:114390660-114391160
  LENGTH = 500  COMBINED P-VALUE = 2.39e-06  E-VALUE =  0.00048
  DIAGRAM: 3-[+2]-[+2]-3-[+1]-173-[+1]-3-[-2]-188

        [+2]                          [+2]                             [+1]
        5.2e-06                       4.5e-07                          7.0e-05
        TTGCTCCTCTCTTTTACCTCTTATCTCTGGTTGCTCCTCTCTTTTACCTCTTATCTCTGG   AGCTGGGTG
        +  ++++++++++ +  ++++   ++++++ + +++++++++++ ++ ++++ + +++++      ++++ +
1    GGGTCTCCCCTTCTCTGTGACCCTGGCCTCTGGATCCTGCTGTCTCTCCCGCCTTCTGTCTGTGCGCCTTGGGCG

     
     
     TGGCCGGGGGT
     +++++ + + +
76   GGGTCCCTGCTGGATAGGAAGGAACGCGGGACTAGGGTGGCCCCTCCCAATGCTAAGTAGAAACAGACGCCCAAA

                                       [+1]                   [-2]
                                       3.5e-07                2.0e-05
                                       AGCTGGGTGTGGCCGGGGGT   CCAGAGATAAGAGGTAAA
                                       +++++++++++ ++ +++++   ++++++ + ++++++
226  GCGTGACTAAGAGGTCCCCTTGCCCCTGCTGAGGAGAAGGGTGTGCCCAGGTTTAGTGCAGAGGTCAGAGGACTT

     
     
     AGAGAGGAGCAA
      +++ +++   +
301  TAACTGGGTTTACCTAACCTTAGATCCTCCAGACTTGTTCTCCTCCACTCTCAAGTCTGAAGGCCTCCTCCTCTC


chr12:27135944-27136444
  LENGTH = 500  COMBINED P-VALUE = 4.25e-06  E-VALUE =  0.00085
  DIAGRAM: 275-[-1]-89-[+2]-4-[+2]-52

                                                       [-1]
                                                       2.6e-08
                                                       ACCCCCGGCCACACCCAGCT
                                                       ++ +++++++++++++++++
226  GAGGCTGAGAAAACCCAGATAAAGAGGAACTGGGCATAGGAACCACCATTCAGCCAGGCCCCACCCTGCTAGCTC

              [+2]                              [+2]
              6.4e-05                           1.1e-05
              TTGCTCCTCTCTTTTACCTCTTATCTCTGG    TTGCTCCTCTCTTTTACCTCTTATCTCTGG
              ++ ++++ +++++++++++    +++ +++     + +++++++++++ + ++++ +++ ++++
376  CTTTACTGGTTTCTGCAGCTTCCATTTTTACCTCTGTGTCCTGGGACCTCTCTCTTCCTGTCCTGATCCCTGCCC


chr10:59256089-59256589
  LENGTH = 500  COMBINED P-VALUE = 3.47e-05  E-VALUE =   0.0069
  DIAGRAM: 247-[+2]-17-[-1]-186

                           [+2]                                           [-1]
                           4.9e-06                                        5.6e-0
                           TTGCTCCTCTCTTTTACCTCTTATCTCTGG                 ACCCCC
                           ++++++ ++++++ +++++ + + ++++ +                 +   ++
226  NNNNNNNNNNNNNNNNNNNNGCTGGCCTTTCTTTCATTCTCATCAGCTCTATCAGAGTCCATGTGATAGAGGAGA

     
     7
     GGCCACACCCAGCT
     ++ +++++++++ +
301  GGACACACCCATATCACAGGTGGAGACACTGATACTGTCGACAGCCACAGCTGCTGTGTGGTAGTGTCTGCTCGG


chr4:135733850-135734350
  LENGTH = 500  COMBINED P-VALUE = 3.87e-05  E-VALUE =   0.0077
  DIAGRAM: 183-[-1]-263-[+2]-4

                                      [-1]
                                      3.2e-06
                                      ACCCCCGGCCACACCCAGCT
                                       +  + ++++++++++++ +
151  GCACTGAGCCAGGAAGTCCCCTGGGCCTGGGCGGATGCTGGCCCCACCCTGATAAGGGCCAGCTGTGGAGCTGTG

                     [+2]
                     9.6e-07
                     TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                     +  +++ +++++++ +++++ + + +++++
451  GGAAGGCCTGATTCTCTAACTCTTTCTCCCCCCCCCCTCTGTCTGTCAAA


chr1:137838164-137838664
  LENGTH = 500  COMBINED P-VALUE = 4.56e-05  E-VALUE =   0.0091
  DIAGRAM: 192-[-2]-1-[+1]-44-[-1]-193

                                               [-2]                           [+
                                               3.9e-05                        9.
                                               CCAGAGATAAGAGGTAAAAGAGAGGAGCAA AG
                                               ++ +++   +++++++++ +++ +++   + ++
151  TATGATGGGGCCACCAGGCACATACAGGGACCTTTACAAAAGCCTGAGGAGAGAAGATAGCAGCTGCATGGAGAG

     1]                                                            [-1]
     6e-08                                                         4.1e-06
     CTGGGTGTGGCCGGGGGT                                            ACCCCCGGCCACA
     ++++++++++++   + +                                            ++ +++++ +++
226  ATGGGTGTGGCTCTCTCTCCAGCTGGGAGCCCTGGAAGGGACAAGATAGAAGTCCTGTCCAGAAGCCAAGTCACG

     
     
     CCCAGCT
     +++++++
301  CCCTTCTGCATATTCACATTTTCCTCAGAATCTTCACAAATCTCCTAACTGGTCTCATCTAGTCATATTCTTGTC


chr17:47735006-47735506
  LENGTH = 500  COMBINED P-VALUE = 5.95e-05  E-VALUE =    0.012
  DIAGRAM: 203-[+2]-15-[+1]-97-[-1]-115

                                                          [+2]
                                                          7.0e-08
                                                          TTGCTCCTCTCTTTTACCTCTT
                                                          ++++++  ++++++  +++ ++
151  ATCTCCAGCAGAGGGCACCATCCACCCGGGCCCCCAACTATGATTGTACGCCCTTGCCTGCTTCTCTGGCCTTTT

                            [+1]
                            7.3e-05
     ATCTCTGG               AGCTGGGTGTGGCCGGGGGT
     ++++++++               +  ++++++++++   ++
226  ATCTCTGGCTCCAGTCTGGAGAGGAGTGGGTGGGGTGAAGGACACTTGGCATGTAGATACCCTTCTCTTGACATC

                                                                      [-1]
                                                                      7.6e-05
                                                                      ACCCCCGGCC
                                                                      +++++  +++
301  TCTTGACAAGTGCTGTGTCTCGGACAGGGGTGGGGGACTTGGTGTCAGATGGAGGGTTGCTCTCACACCCTTGCC

     
     
     ACACCCAGCT
     +++ +++  +
376  ACATCCTCTTGCCAGTTTCTGAGAACTAAAGACCTGATTCCTGGGCTGGGCTGTGGCCTAACCTCCCCAGACTTC


chr6:72223026-72223526
  LENGTH = 500  COMBINED P-VALUE = 6.80e-05  E-VALUE =    0.014
  DIAGRAM: 52-[-2]-7-[+2]-162-[-1]-42-[-1]-137

                                                         [-2]
                                                         3.0e-05
                                                         CCAGAGATAAGAGGTAAAAGAGA
                                                         +++ + + ++++++++ ++  +
1    ACAAAGTTAGAGACCCAAAGAAGAAAGGTTTGGTCTCTTCTTCCATCAGAATCCACACACAAGGGAAATGGTTAG

                   [+2]
                   1.9e-05
     GGAGCAA       TTGCTCCTCTCTTTTACCTCTTATCTCTGG
     +++ + +        +  ++   ++++++++ +++ ++++++++
76   GAGTCGAACAACCACTAATCTAATCCTCATTACCTAATCTCTGTCACCTGCTCTTGGGAGGCCGGGGAGAAGGAC

                                                             [-1]
                                                             6.2e-05
                                                             ACCCCCGGCCACACCCAGC
                                                              ++++++ + ++++++++
226  GATCCCATGGAGCCAGCTCTTGTTTGGTCAGTCTTGTCTACCCATCTTCCTGCCCCTCCCCCACCACCACCCTGA

                                                [-1]
                                                3.0e-07
     T                                          ACCCCCGGCCACACCCAGCT
     +                                          +++ ++ +++++++++++++
301  TTACGGGGCATGCCCAGTTCACTTACCAGACCTCACAGCCGACCCCACCCACCACACCCATCCCAGACAGCACTC


chr13:3866266-3866766
  LENGTH = 500  COMBINED P-VALUE = 6.97e-05  E-VALUE =    0.014
  DIAGRAM: 241-[+1]-2-[-1]-217

                     [+1]                  [-1]
                     8.0e-05               4.9e-08
                     AGCTGGGTGTGGCCGGGGGT  ACCCCCGGCCACACCCAGCT
                     + +++++ +++ +++ +  +  ++ + +++++++++++++++
226  CCTTTCCAGTGTGATTATCAGGGCGGGTTTGTACCTAGCCGTTCAGCCACACCCTTCTGGGTTGGTCCTGTTTGG


chr1:133343883-133344383
  LENGTH = 500  COMBINED P-VALUE = 9.75e-05  E-VALUE =     0.02
  DIAGRAM: 190-[+2]-15-[+1]-245

                                             [+2]
                                             8.3e-05
                                             TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                                 +++ + + + +++++ ++++++++
151  CATTGCAGACTTGGGCCCAGAGGCTCCTGTGGGTGACTGGACATATCAGGCATGTTCCCATTATCTCTCATAAGC

               [+1]
               1.1e-07
               AGCTGGGTGTGGCCGGGGGT
                + +++++++++++++++++
226  ACTGGGTAGTTGTAGGGTGTGGCCTGATTGATCATGGCAGCATACTTGGTGTTGTGGGCTAACCATGGGGATAAT


chr11:117187372-117187872
  LENGTH = 500  COMBINED P-VALUE = 1.01e-04  E-VALUE =     0.02
  DIAGRAM: 242-[+1]-46-[-2]-71-[+1]-71

                      [+1]
                      4.1e-07
                      AGCTGGGTGTGGCCGGGGGT
                      +++ ++++++++++++++ +
226  CATGGCCTGTAGAGGGAGGAGGGGTGTGGCCTCAGAGAACCCACTGGAGAGATGGATCAAAGCTGGGCAGGGGTT

             [-2]
             3.2e-05
             CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
             + + +   ++++++ ++++++++++++  +
301  GGAACCAGAAACACGGAAGAGGCAGAAGGGAGGGGAGATCACGCCCGGAAGCCAAAATGAGATGTGAAAGGGAAA

                                       [+1]
                                       2.8e-07
                                       AGCTGGGTGTGGCCGGGGGT
                                       +++++++++++ ++++++ +
376  GAGATCCCAGGATGGTCCCGCAAGGGCTGCCTCAGGCTGGGTGTGACTGGAGATGAGCCAGTGGGGAACCTCCCA


chr13:76003199-76003699
  LENGTH = 500  COMBINED P-VALUE = 1.11e-04  E-VALUE =    0.022
  DIAGRAM: 230-[+2]-15-[+2]-60-[-1]-115

          [+2]                                         [+2]
          3.3e-07                                      1.0e-05
          TTGCTCCTCTCTTTTACCTCTTATCTCTGG               TTGCTCCTCTCTTTTACCTCTTATC
          +++++++ + ++   ++ ++++++++++ +               ++++++  ++++++ + ++++  ++
226  CCTCTTGGCACCAGGTTGACTCATCTTATCTCTCCTTAGCAGGTCTTCTCTTGCTTTCCCTCCCCTGCTCTCCTC

                                                                      [-1]
                                                                      3.0e-05
     TCTGG                                                            ACCCCCGGCC
     ++  +                                                            +   + ++++
301  TCATGGTCTGGTTTAGTCAGCTGGCCATGTTCAGCCTGGCTCTTCCTTCTCTCTTTTCTACACTAAGGAGTGGCC

     
     
     ACACCCAGCT
     +++ +++ ++
376  ACATCCTCCTCTGCTCATTTCATTTTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN


chr5:65202593-65203093
  LENGTH = 500  COMBINED P-VALUE = 1.19e-04  E-VALUE =    0.024
  DIAGRAM: 24-[-2]-36-[+2]-193-[-1]-11-[+1]-10-[+1]-106

                             [-2]
                             4.6e-05
                             CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                             ++++ ++   ++++++++++++ +++++
1    GTTAAGGAGGGGCAACCTCTTAGAACAGGGACTGGAGGGAGGAGGAGGAGGCTTGGGCTGGACTGGAGCCATGTT

                    [+2]
                    9.6e-05
                    TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                        ++++++++  +++ + ++  ++++++
76   GCCCAGCCAAGGTTGCAAGTGCTTTCTGGTTTGTGTTTACTCTGGAAGGGGAGGGCACCTCCCCCCCCCCCCCCC

                  [-1]                           [+1]                          [
                  3.1e-05                        2.3e-07                       1
                  ACCCCCGGCCACACCCAGCT           AGCTGGGTGTGGCCGGGGGT          A
                  ++ ++ ++ +++ +++++++            +++++++++++++ +++++          +
301  TTCAGCTTGGAGCCAGTCGGGTCCCTCCCAGCCTTCCCACTCCCTGCAGGGTGGGGCCCCATGGGTGGAGGCCCA

     +1]
     .7e-05
     GCTGGGTGTGGCCGGGGGT
     +++++++++ ++  +++++
376  GCAGGGTGGAGTGAGGTGGGTCTCCAGTGATAGGGAGGGCACCTAGTGAGCCAGGCAGATGAGAGGCCCCGTGGC


chr14:79702844-79703344
  LENGTH = 500  COMBINED P-VALUE = 1.30e-04  E-VALUE =    0.026
  DIAGRAM: 247-[-1]-46-[-2]-157

                           [-1]
                           5.6e-07
                           ACCCCCGGCCACACCCAGCT
                            ++   ++++++++++++++
226  TGTCTCTTTTCAGCACCACTTTGAAGTTAGCCACACCCTGCCTCCCTAGGGTGAAGAAGAACTAAGCAGTCAAGG

                  [-2]
                  2.1e-05
                  CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                  ++++++   + +++  ++ +++++++ +++
301  GTGGCACTGAGCCCCAGAGCAGATAAGCCAACAGCAGCAACCAATCTGGGAGGAGCAGCCNNNNNNNNNNNNNNN


chr12:112796794-112797294
  LENGTH = 500  COMBINED P-VALUE = 1.31e-04  E-VALUE =    0.026
  DIAGRAM: 232-[+1]-41-[+1]-187

            [+1]                                                         [+1]
            6.9e-06                                                      7.3e-08
            AGCTGGGTGTGGCCGGGGGT                                         AGCTGGG
            + +++++++++ ++++++                                            + ++++
226  CTAAAGGGCCTGGGTGTGACTGGGTACATCTGGCAGGTTCCCATTATCTCCTATGGACACTGTGAAGTTGTAGGG

     
     
     TGTGGCCGGGGGT
     +++++++++++++
301  TGTGGCCTGGTTGACAGTGGTGGCTCTCAGTTAGGGGCTGAGTGAGGGAAGAATTACGACTGGAAATGAGCAGTT


chr13:112863645-112864145
  LENGTH = 500  COMBINED P-VALUE = 1.61e-04  E-VALUE =    0.032
  DIAGRAM: 228-[+1]-20-[-1]-212

        [+1]                                    [-1]
        3.0e-05                                 3.5e-07
        AGCTGGGTGTGGCCGGGGGT                    ACCCCCGGCCACACCCAGCT
        ++ +++++++ +++  + ++                    +++++ +++++++++++  +
226  CCAGGTAGGGTGGAGCCCAGATGTGAGCTCCTCTAGCTGCTCACACTCTGACCACACCCAAATCTGCATATGGAA


chr7:111007530-111008030
  LENGTH = 500  COMBINED P-VALUE = 1.83e-04  E-VALUE =    0.037
  DIAGRAM: 217-[+1]-83-[+2]-150

                                                                        [+1]
                                                                        2.3e-07
                                                                        AGCTGGGT
                                                                        ++++++++
151  TTTTATTTAAATAAGTAGAAGTAGAAAGAACTGGTGTTTTTCTTCTTCTGGGACTTGGGGTAGTGTCAGCTGGGT

     
     
     GTGGCCGGGGGT
     ++++++ +++
226  GGGGTCACAGACTGTGGTGACAGATAAGAGCCAGAGCTGCACAGAGCTGAGTCAAGGTTGAGGCCTCCGTGAGAT

                         [+2]
                         7.4e-05
                         TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                          ++++++++++++++++ ++  +++  +++
301  TGGGGGAAGCCAGTGTGTTTGGGCTCCTGCCTTCTTTGTCCCATCATTGCTCCTTCATGAGTAGATAAGAGGTAT


chr1:43307690-43308190
  LENGTH = 500  COMBINED P-VALUE = 1.91e-04  E-VALUE =    0.038
  DIAGRAM: 164-[-2]-52-[-2]-224

                   [-2]
                   8.0e-05
                   CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                   + + ++  ++++ + +++++ +++++  ++
151  AGGCTTTACAGGTAAAACAGCAAAGATACAAAGGCAAGAATGAAGCCATTCTATTCACGAGAACTCAAAAGGGAC

                          [-2]
                          7.8e-08
                          CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                          +++++ +  + +++++++++++++++++++
226  TAAACCCACCAAACCATTGTGCCAGACACTATAGGAAGGAAGAAGGAGCCAAACCACCATGTTGGCTCATGTTCA


chr14:47973722-47974222
  LENGTH = 500  COMBINED P-VALUE = 2.00e-04  E-VALUE =     0.04
  DIAGRAM: 21-[+1]-181-[+1]-20-[-2]-208

                          [+1]
                          2.3e-05
                          AGCTGGGTGTGGCCGGGGGT
                          + +++++ +++++++++  +
1    CATAGTTTGACTCCAAACTGTGCCTGGGAGGGGCCTGGAATGAATGAACTGCTGGGGAGGGGACAGCGGCTTGCT

                                                                             [+1
                                                                             5.2
                                                                             AGC
                                                                             + +
151  GCCAGGTTACTGCCAGTACAGCCACAGGGGGGGGCATGGAAAAACACCCGTGCCTCTGAGCCATGCTGAGTCATC

     ]                                    [-2]
     e-05                                 8.3e-07
     TGGGTGTGGCCGGGGGT                    CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
     ++++ ++ + + + + +                    + ++++ +++ +++++  ++++++++ + +
226  TGGGCGTAGGCACTGCTGGGTTTCATTCTTGCAACATAAAGAGCTAACAGAGTCCAGACAGAATCTAGCCTGGGT


chr9:120025371-120025871
  LENGTH = 500  COMBINED P-VALUE = 2.32e-04  E-VALUE =    0.046
  DIAGRAM: 110-[-2]-58-[+1]-282

                                        [-2]
                                        2.3e-05
                                        CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                         +++++++  ++++++++++ + ++
76   GTGAAACCAGAGGGGCCCCTTTTGCTGTGTACATTTCAGAGATGGGGAGATAGAATGGGGCTGTGACAGGTGGAG

                                                     [+1]
                                                     9.3e-07
                                                     AGCTGGGTGTGGCCGGGGGT
                                                     +++++++++++++ ++  +
151  CCTGAAGGATCTCAGAGGAGAAACCACAGATGCATATGTGGAGAAAGGAGCTGGGTGTGGTGGGCCGACCTGCTG


chr7:105490727-105491227
  LENGTH = 500  COMBINED P-VALUE = 2.43e-04  E-VALUE =    0.049
  DIAGRAM: 100-[-2]-111-[-1]-239

                              [-2]
                              2.0e-05
                              CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                              + +++++ +++++++ ++   +  +++
76   CATGTCAACACAAATCGTTCTAAGAGGAGAGAAAAGAGGGCAGTTTGGAGGGGGGCTTGTGACATACATCCCTGC

                     [-1]
                     1.1e-06
                     ACCCCCGGCCACACCCAGCT
                     +++ ++ ++++++++++ ++
226  GTTCTAAGACCTGAACCACACCCACCACACCCACCCATGTGAAAGTTTAAAGATTATGTAATCCTAAAGCTAAAC


chr5:37127175-37127675
  LENGTH = 500  COMBINED P-VALUE = 2.90e-04  E-VALUE =    0.058
  DIAGRAM: 234-[-2]-24-[+1]-192

              [-2]                                                  [+1]
              1.2e-05                                               2.4e-06
              CCAGAGATAAGAGGTAAAAGAGAGGAGCAA                        AGCTGGGTGTGG
              +++++ + ++  ++++ + ++++++++++                         + ++++++++ +
226  TCTGTAGTAGCAGAAAGAAATGGAACGTGGGAGGGGCACAGTGAGGACAGCTTGGGAGCCCAGATAAGGGTGGAG

     
     
     CCGGGGGT
     ++++ ++
301  CCTGTGTCCTGAGCCAACTCTGGAAGCCATCTTGGAGGGCAGGGCTGGTGGCGGCAGGCTGGCCCTGGAGAAAAT


chr5:45951565-45952065
  LENGTH = 500  COMBINED P-VALUE = 2.90e-04  E-VALUE =    0.058
  DIAGRAM: 261-[-1]-219

                                         [-1]
                                         1.4e-07
                                         ACCCCCGGCCACACCCAGCT
                                         ++++  ++++++++++++ +
226  TTTATCTGGACATTTACTAACCTTGGTGGGGACACGCCCCAGAGCCACACCCAGGTCTGGCAATCATCTGCATGC


chr7:91033422-91033922
  LENGTH = 500  COMBINED P-VALUE = 3.06e-04  E-VALUE =    0.061
  DIAGRAM: 465-[-1]-15

                    [-1]
                    2.1e-07
                    ACCCCCGGCCACACCCAGCT
                    +++ + +++++++++++  +
451  AGAAGGTCCCCTAAACCCACTGGCCACACCCACTCCCTTTCTTTGTGCAG


chr4:154285745-154286245
  LENGTH = 500  COMBINED P-VALUE = 3.21e-04  E-VALUE =    0.064
  DIAGRAM: 235-[+1]-20-[-2]-195

               [+1]                                    [-2]
               4.6e-06                                 6.7e-06
               AGCTGGGTGTGGCCGGGGGT                    CCAGAGATAAGAGGTAAAAGAGAGG
               +++++++++++ +++++                       ++++++++ + ++++ ++   ++ +
226  GTTGGGGTGGGGCTGGGTGGGACTGGGCACAGTGTTATCAATAGTGCCAGCCAGAGATCACAGGACAACTTGAAG

     
     
     AGCAA
     +   +
301  GAGTATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN


chr13:100518008-100518508
  LENGTH = 500  COMBINED P-VALUE = 3.56e-04  E-VALUE =    0.071
  DIAGRAM: 226-[-2]-18-[-1]-206

      [-2]                                            [-1]
      7.5e-07                                         4.7e-05
      CCAGAGATAAGAGGTAAAAGAGAGGAGCAA                  ACCCCCGGCCACACCCAGCT
      +++++++ +++++++  ++++ + +    +                  + +  ++++ ++ +++++ +
226  GGCAGAGAAAAGAGGTGTGAGATAAACAGGAGCGGAGTCGAGATTCTGCAGAAACAGCTCCGCCCAGTTCCGCCC


chr1:36977019-36977519
  LENGTH = 500  COMBINED P-VALUE = 3.71e-04  E-VALUE =    0.074
  DIAGRAM: 88-[+1]-187-[+2]-60-[-1]-95

                  [+1]
                  2.9e-05
                  AGCTGGGTGTGGCCGGGGGT
                  +++++ +++++ ++++++
76   CCTTGAGAGGAGCAGCAGTGTGTGCCTGGATAAACAAACACTGCTGTTCTAGCACCAGGTCCTCCCAGGCACTAG

                                                                           [+2]
                                                                           2.2e-
                                                                           TTGCT
                                                                           ++  +
226  ACTTAAATGCCTATCTTATGTTTTCAAAACCATTTCCTTTACAGATCCTCATTACTGAGCCTTTCAAGCCTTCTC

     
     06
     CCTCTCTTTTACCTCTTATCTCTGG
     +  + ++++ + + +++++++++++
301  TGCTATCTCCAATGCTTATCTCTGGGCTGGCACGCCTCTTGATAGGCTGCCATTGAGTCTGAGTGCAGTCCTGCA

               [-1]
               1.7e-05
               ACCCCCGGCCACACCCAGCT
               + ++    +++++++++ ++
376  GTGAGTCAGAATCTATCTCCACACCCACCTGGTGAAGACTGTTCCATCCTTCTCTATAGACAGTCTGCTCACAGG


chr7:151917814-151918314
  LENGTH = 500  COMBINED P-VALUE = 3.94e-04  E-VALUE =    0.079
  DIAGRAM: 219-[+1]-80-[+2]-151

                                                                          [+1]
                                                                          5.6e-0
                                                                          AGCTGG
                                                                            ++++
151  GGAGGCGGAATGGTGAACAATGCTGGGTGCTGGGCTGGGGAAAGATAGGAGACTATGGTGAGCCCTGCCTTCTGG

     
     7
     GTGTGGCCGGGGGT
     ++++++++ + ++
226  GTGTGGCTCCCTGCAGCAGCCAGATAGTCACAGATAACTTTCTTTTCCTCCAAAGCCAGCGACCCCAGTTCTGGG

                        [+2]
                        7.1e-05
                        TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                         + +++   +++++  ++++   +++++++
301  GCCCAAGCTGAATTCCAGACTTCCCTCACCCCTGGCCTCACTTCTCTGTATCCAAGCCTCCATGAATCAGGCTAG


chr7:110976195-110976695
  LENGTH = 500  COMBINED P-VALUE = 4.09e-04  E-VALUE =    0.082
  DIAGRAM: 287-[+2]-12-[+1]-151

                                                                   [+2]
                                                                   3.1e-05
                                                                   TTGCTCCTCTCTT
                                                                   +++++++++++++
226  CAACTATGTCAGAAGCAAATGTGAGGAGCAACTGATCCTACCTCACCTTATATGCTCTGCCCTGGCTCCTGCCCT

                                  [+1]
                                  1.3e-06
     TTACCTCTTATCTCTGG            AGCTGGGTGTGGCCGGGGGT
     ++++ ++ + + +  ++            + ++++++++++++  + ++
301  CTCTATCCTGTGTGAGCAGATTGGCCCTTACCAGGGTGTGGCTCTACGGAATCAGGCTTCGGTGATGACAAGCAT


chr15:58719281-58719781
  LENGTH = 500  COMBINED P-VALUE = 4.76e-04  E-VALUE =    0.095
  DIAGRAM: 212-[-2]-258

                                                                   [-2]
                                                                   3.1e-07
                                                                   CCAGAGATAAGAG
                                                                   +++++   +++++
151  TATCGTAATAGCTGATATAGAGGCTTTGGTAAAAGAAAACCGGGGCCTACAGTGCCTCGTATACAGATGGAAGAG

     
     
     GTAAAAGAGAGGAGCAA
     ++ ++++ +++++  ++
226  GGGAAAGTGAGCAAACAAAGCCCAAACCACAAAACTGGGTGGAGGTGCCATCTTCCTGCTCCAAACACCTTCCCC


chr11:57590460-57590960
  LENGTH = 500  COMBINED P-VALUE = 5.00e-04  E-VALUE =      0.1
  DIAGRAM: 56-[-1]-271-[-1]-75-[+2]-28

                                                             [-1]
                                                             9.0e-05
                                                             ACCCCCGGCCACACCCAGC
                                                               +++++++ ++ ++++ +
1    GTTTTCCTTTCCCCACCATCAGAATAGAACTGCGCTGCCCAGACAGCACCCCTGCGTTCTGAAACAACTCCCACC

     
     
     T
     +
76   CTGGGAAATGGCACAAAGGACATCCTACATCTATCCTGGCAGGAGATAGAAAGACCCTCTCACCCTTTGAGAGCC

                                                    [-1]
                                                    8.1e-07
                                                    ACCCCCGGCCACACCCAGCT
                                                     +++  +++++++++++ +
301  CTCCACACCCAAAGCCACTGTGGCCTCCATTCTGGACTGTAGTATCTGCCCAGGACCACACCCACCACGCCCCAT

                                                                        [+2]
                                                                        6.4e-05
                                                                        TTGCTCCT
                                                                           ++++
376  GAGCAGAGCCAACTTTGTAAAGTTGAATGGGATTAAGATATCCTGTCTAGTCATGCCCCGACGAGAGCCCCCCCC

     
     
     CTCTTTTACCTCTTATCTCTGG
     ++++ + +++++++  +++
451  CCCCGCCTTCCCTTCCCTCACAGCCCACTGGGTGCCAGGCCTTCGACGTC


chr8:83025150-83025650
  LENGTH = 500  COMBINED P-VALUE = 5.31e-04  E-VALUE =     0.11
  DIAGRAM: 219-[+1]-87-[+2]-144

                                                                          [+1]
                                                                          4.9e-0
                                                                          AGCTGG
                                                                          +  +++
151  CCATGCCATTGATCTTAAAAGGAAGCCAGTCCCCCACAGTGTTTCTCCACAGATTACTTAGGGGTAGGCAAGAGG

     
     5
     GTGTGGCCGGGGGT
     + +++ ++ + ++
226  GCGGGCCCAGTGGCAGACAGATCCCACTGCCTGCAAAATGATAGCCTATAAGCCAGTTGGGTGATGAGATAAGGG

                               [+2]
                               1.1e-06
                               TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                +  ++++++++++ +++++ ++ ++++ +
301  GTGGGCCTGTAGTACATTCGCTTGAGCGATCTCTCTCCCTCCCTTCCTACCTCTCCCGCTTGTCTAATTTTATAG


chr13:54345922-54346422
  LENGTH = 500  COMBINED P-VALUE = 5.79e-04  E-VALUE =     0.12
  DIAGRAM: 283-[-2]-161-[+1]-6

                                                               [-2]
                                                               3.5e-05
                                                               CCAGAGATAAGAGGTAA
                                                               +++  ++   +++++++
226  CGATGTCAGCTTAGGAGACCATTAGTGGAGAGAGCTTGAGAGATGGTTCTCCCTTTGGCCAATGAGGGGAGAGAG

     
     
     AAGAGAGGAGCAA
      ++ + +++++++
301  CAGTCTGAAGCAAGGCATCCAGAAAGGAGTGTGTCTGCTACTACAGTGTTTATGCTGCTTCTTCTGCCACCGTAG

                             [+1]
                             1.7e-06
                             AGCTGGGTGTGGCCGGGGGT
                             + +++++++++ ++ + +++
451  CCAAGGAGCTAAGTTATGGTACAAGTCAGGGTGTGCCCCCTGGGAGGCTC


chr12:82044358-82044858
  LENGTH = 500  COMBINED P-VALUE = 6.20e-04  E-VALUE =     0.12
  DIAGRAM: 50-[+2]-160-[+1]-39-[+2]-171

                                                       [+2]
                                                       5.3e-05
                                                       TTGCTCCTCTCTTTTACCTCTTATC
                                                         + ++++++++++ ++++     +
1    AGTATTTAATAAGTAAAAGATGGGCTTATAGGGTGAATCTGAGTCAGAAACAGAATCTCTCTCTCTCTCTCCCCC

     
     
     TCTGG
     +++
76   TCTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN

                    [+1]                                                       [
                    2.0e-05                                                    3
                    AGCTGGGTGTGGCCGGGGGT                                       T
                    ++ +++++++  ++ +++++
226  CTCCTAACACCTTCAGGGAGGGTGTAACCCGATTTCTGGGGAGAGGAAGGCAGCTAGCAGGTCTGTGATGGACAA

     +2]
     .1e-06
     TGCTCCTCTCTTTTACCTCTTATCTCTGG
     +  ++ ++++++++++++ + ++++++++
301  TAAATGTTCTCTTAATCTGTGATCTCTGTAACTCTTTTCCTCTACTACATATATGTTATTTGTTTGAATGTCTTT


chr11:105013714-105014214
  LENGTH = 500  COMBINED P-VALUE = 6.68e-04  E-VALUE =     0.13
  DIAGRAM: 115-[-2]-160-[+1]-26-[-1]-129

                                             [-2]
                                             2.4e-05
                                             CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                             +++ +++ +  ++ + +++++++++++ ++
76   ATTAGAGAATTCTGGTCCTTAGGAGACACACTTTTCTGCACCACAGACACTAACAGGAAAGCAGGAGGAACACTC

          [+1]                                          [-1]
          2.9e-06                                       1.8e-05
          AGCTGGGTGTGGCCGGGGGT                          ACCCCCGGCCACACCCAGCT
          +++++++++++ ++   +                            +++ + +++ ++++++++++
301  GTGTCAGATGGGTGTGCCCCTTTCACCAGAGGCCCACACGGCCCCCCAGGGCACAGTGACACCACCCTTCCTGAA


chr10:93585404-93585904
  LENGTH = 500  COMBINED P-VALUE = 7.22e-04  E-VALUE =     0.14
  DIAGRAM: 141-[+2]-48-[+1]-261

                                                                       [+2]
                                                                       3.9e-05
                                                                       TTGCTCCTC
                                                                         +++++++
76   AGAAGGGGTTGTCAGCATCTCTGTGGAGATGGCATGGAGCCAGAAGGTTTAGCATCAGGTGACCAACAGCAGCTT

                                                                          [+1]
                                                                          2.0e-0
     TCTTTTACCTCTTATCTCTGG                                                AGCTGG
     +++++++++++    ++++                                                  ++++++
151  CTTTTATCTTCCATCCTCTCAGTCCTAAGGTTCTCAGCCCTGCTCACTACAGATTGCAGCAAGCCAGAGAGATGG

     
     6
     GTGTGGCCGGGGGT
     + ++  ++ +++++
226  GCGTATCCAGGGTGACCGTGAGGATGGCGGGGGAGATAGTGTCAGGCGCATAAGTTCTGGCCTATGGTGGGGATT


chr7:19832207-19832707
  LENGTH = 500  COMBINED P-VALUE = 7.99e-04  E-VALUE =     0.16
  DIAGRAM: 229-[-1]-251

         [-1]
         3.2e-07
         ACCCCCGGCCACACCCAGCT
          ++++++++++++++++
226  AAAAGCCCCAGGCCACACCCAAGATGTCTGACTATAGGTAACAGGTTCATTCTCCCTGGCCCTTGTCCCTAGAGG


chr8:97323995-97324495
  LENGTH = 500  COMBINED P-VALUE = 1.03e-03  E-VALUE =     0.21
  DIAGRAM: 177-[-1]-40-[-2]-139-[+1]-74

                                [-1]
                                1.6e-06
                                ACCCCCGGCCACACCCAGCT
                                  + + +++++++++++ ++
151  NNNNNGGGTCGAGGAGATCACCTAAGAGGAAGGAGCCCCACCCACCCCTGCTCCTATGGGAAGAAGGCAAGGTGG

                 [-2]
                 7.1e-05
                 CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                 +  +++   + ++++++ ++++++++  ++
226  AAGAACTGTCTTGGCGAGGAGATGGGGAGCAGAGAGAATGCATGGGACAGATGTCCATCTTCCCTAGGTAATCTG

                                    [+1]
                                    4.9e-05
                                    AGCTGGGTGTGGCCGGGGGT
                                    +++++++++++   ++++
376  GCTGAGAGCTGGAAGGAGCCCAGGCGTGGCAGGAAGGGTGTGCAAGCAGCAGCAGGCAAAGCCAGGCAAAGCAGG


chr10:126642277-126642777
  LENGTH = 500  COMBINED P-VALUE = 1.16e-03  E-VALUE =     0.23
  DIAGRAM: 252-[-1]-92-[-2]-106

                                [-1]
                                5.5e-06
                                ACCCCCGGCCACACCCAGCT
                                      ++ +++++++++ +
226  NGCGGTTTTAGACGATGCGTGCCCAGTGGGAAGAGACACACCCAGTTTCTGTTAAGTCAAACAGAAGCAAGCAGT

                                                                     [-2]
                                                                     2.3e-05
                                                                     CCAGAGATAAG
                                                                     + +++++ +
301  GAGGCCCTCCTGCTGCTGCTGTACTTCCTAAGTGTGTAAAGAGAAGATAAGCAGTGCTTCTGAGGGAGAGACAGC

     
     
     AGGTAAAAGAGAGGAGCAA
       ++++ +++++++++  +
376  CTATAGCAAGGAGCAGGGAAGCTGTGGGCTCTGCCAGCCTTGCGCACACAGTGGGACAGCTGGGCTGGAGAGGCC


chr1:156887119-156887619
  LENGTH = 500  COMBINED P-VALUE = 1.19e-03  E-VALUE =     0.24
  DIAGRAM: 189-[-2]-78-[-1]-183

                                            [-2]
                                            6.9e-05
                                            CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                              +++++ ++++  ++++  ++  ++++ +
151  NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGCTTTAGAGACAAGATTAAGACTAAGACAGCGACTGCAA

                                                                             [-1
                                                                             2.0
                                                                             ACC
                                                                              ++
226  AGCACCTGACATGCTAGAGACGCCCAACTGACTATCAACGCAATGAACATCCTGTTCACACTCAACCCCCATTCA

     ]
     e-06
     CCCGGCCACACCCAGCT
      + +++++++++++ +
301  GGTGACCACACCCAACAAGCTGGGCCAAGACGACTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAC


chr15:81700367-81700867
  LENGTH = 500  COMBINED P-VALUE = 1.25e-03  E-VALUE =     0.25
  DIAGRAM: 109-[-1]-99-[-1]-252

                                       [-1]
                                       3.1e-05
                                       ACCCCCGGCCACACCCAGCT
                                        + +     +++++++++ +
76   NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACACACCCATTCGCAGGAGACAGCAAGGTACAT

        [-1]
        1.4e-06
        ACCCCCGGCCACACCCAGCT
          ++ +++++++++++++ +
226  TCTTTATTAGACCACACCCAGTTTGGCTCACAGGCTTGAAGAAATTACCTAGATAACTAGCTGAACACTGCAATC


chr6:121187425-121187925
  LENGTH = 500  COMBINED P-VALUE = 1.27e-03  E-VALUE =     0.25
  DIAGRAM: 29-[+2]-313-[-1]-108

                                  [+2]
                                  8.0e-05
                                  TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                   + +++   +++++++++ +++ +++  ++
1    TCACATTGAAAATGGATCCCTGTAATTTACTTCTTGCATCTTCTTCTACTTGTCTGAGGATAGTTTCTCGTCAAA

                                                                             [-1
                                                                             1.8
                                                                             ACC
                                                                             +
301  GCTGAGCAGTAGTGGGTTTCTAACATTACTTGCTTACATATACACTGGTCCAGTGCATGGTTGTTTGGGAAGATG

     ]
     e-06
     CCCGGCCACACCCAGCT
     + +++++++++++++ +
376  CTAAGCCACACCCTGGCCTTAGAAACACCATGCCGCTGAGATGAATTGTCCCTAGGATGGCACCCAGGGAAATAA


chr4:43977111-43977611
  LENGTH = 500  COMBINED P-VALUE = 1.53e-03  E-VALUE =     0.31
  DIAGRAM: 60-[+1]-148-[+1]-252

                                                                 [+1]
                                                                 6.2e-05
                                                                 AGCTGGGTGTGGCCG
                                                                 ++++++++ ++ +++
1    GAGATCTCCAAGGCTCAGTGGGAAACAAGCAGGAGAAAGTATAAGCCCAGCCTCGGGGGCAGATGGGTCTGCCTG

     
     
     GGGGT
     + + +
76   CTTCTCCTCTAGCTCCTCAGCAAAACTAAAAGTGGATCCCTGCCCTTCCCCCATCATGGGCAGCTGAGGGCCCTC

        [+1]
        3.0e-07
        AGCTGGGTGTGGCCGGGGGT
        ++++++++++++++++  ++
226  CCTGGCTGGGTGTGGTCGCCAGTGATAACTTGCCTCCTAAGGCTCTTGCCCTGCTCAGACTGAGAGGGGACTCCT


chr11:102236405-102236905
  LENGTH = 500  COMBINED P-VALUE = 1.57e-03  E-VALUE =     0.31
  DIAGRAM: 10-[+2]-145-[-1]-3-[-1]-6-[+2]-60-[+1]-156

               [+2]
               8.3e-05
               TTGCTCCTCTCTTTTACCTCTTATCTCTGG
               ++  +++ +++++++++ ++ + ++ ++++
1    AGAAGGCTTATGTGACCAGCCTCCTCTGTCCTGTCCCTGCCCTTCCTTGGAATCCCCTAGGTTTCCTGTCTCTGG

                                        [-1]                   [-1]
                                        4.9e-05                2.7e-05
                                        ACCCCCGGCCACACCCAGCT   ACCCCCGGCCACACCCA
                                         ++   ++ ++++++++  +   +    +++++++ ++++
151  CTGCCTATATTGATGAAAAAACCCGAGTTCTCCTAGAAAAGGGTCACACCCTAACAGGAGGGACAGCCCCTCCCT

              [+2]
              2.3e-05
     GCT      TTGCTCCTCTCTTTTACCTCTTATCTCTGG
     ++        ++++++ ++ +++ ++++ +  + +++++
226  TCAGAACAGCTGCAGCCCCACTTGATCTGTCGTATCTGCTGAGCCAGATGTTTGAGGTCCTCAACCTGACAGCTG

                             [+1]
                             7.7e-06
                             AGCTGGGTGTGGCCGGGGGT
                               +++++++++ ++ + +
301  ATGGCAGAGTCACAGAGCCCAAGCCTATGGGTGTGTTCCCTGCCCTGTGTATGTCTAGGGGAAAAAGCTTAACAC


chr17:5112057-5112557
  LENGTH = 500  COMBINED P-VALUE = 1.62e-03  E-VALUE =     0.32
  DIAGRAM: 249-[+1]-231

                             [+1]
                             7.5e-07
                             AGCTGGGTGTGGCCGGGGGT
                             +  +++++++++++  ++++
226  TGACCCGTGATAAGAGCAAAACATGTGAGGGTGTGGCTCAGGGTTCCTGTCTGTGCTTAGTAGGGCCTTGCCTGC


chr10:110604369-110604869
  LENGTH = 500  COMBINED P-VALUE = 1.64e-03  E-VALUE =     0.33
  DIAGRAM: 232-[+1]-248

            [+1]
            1.0e-06
            AGCTGGGTGTGGCCGGGGGT
             ++++++++++++ +  + +
226  TCTGAGACGCTGGGTGTGGCATTTGCTGGTGATCCTGCTCTTGGGAGATAGGGAAAGGAGGGTTACCTTGAGTTT


chr1:169314208-169314708
  LENGTH = 500  COMBINED P-VALUE = 1.76e-03  E-VALUE =     0.35
  DIAGRAM: 192-[-1]-[-1]-11-[-2]-227

                                               [-1]                [-1]
                                               7.7e-06             6.1e-06
                                               ACCCCCGGCCACACCCAGCTACCCCCGGCCACA
                                                 + +++ ++++++++++ ++ ++ + ++++++
151  GGCCTCTGGGTCAGGGTGCACCAAGAAGGAAAGGCAGCTCAGTTCAGAATCCACACCCAGGCAGCCTCTGCCACA

                       [-2]
                       3.4e-05
     CCCAGCT           CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
     +++++             ++++++  +  ++++++   ++++++ ++
226  CCCTGGGTTGTTCCGAATGCAGAGGCAGCAGATAGCTTACAGGGCCAGGCCTGAGGAGCTGATAATTGGGAAAAG


chr9:57618594-57619094
  LENGTH = 500  COMBINED P-VALUE = 1.80e-03  E-VALUE =     0.36
  DIAGRAM: 125-[+2]-151-[-1]-4-[-1]-150

                                                       [+2]
                                                       4.1e-06
                                                       TTGCTCCTCTCTTTTACCTCTTATC
                                                          +++++++++   ++++++  ++
76   ATCCAACTGCTCTTCACCTGGGCTAGGTAACCCTCAGGACCCGATAGACAACCCATCTCCTTAGCCTTCCTGCTC

     
     
     TCTGG
     +++++
151  TCTGGCATTCTATAACAGAGCCCCTGGTACAGCTGTCCTGAGCTCTGGAGCCCTCTGCAGCTACAAGGGAGAGGT

           [-1]                    [-1]
           5.2e-05                 5.6e-05
           ACCCCCGGCCACACCCAGCT    ACCCCCGGCCACACCCAGCT
              + + +++++++++++++     +    ++++++++++   +
301  TCCACCTTTCTCCACCCCACCCTTCCCCAAGCTATGAGCCACACCCCCTTGTGTACAAGCTATGACTCAAGACTC


chr10:128184604-128185104
  LENGTH = 500  COMBINED P-VALUE = 1.88e-03  E-VALUE =     0.38
  DIAGRAM: 30-[-2]-128-[+1]-292

                                   [-2]
                                   1.4e-05
                                   CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                   +++++ +   +++++ ++++++  ++++++
1    GAGTTAAGGAAAAAGCTTTGTAGGAGGAGGGCAGACACCTGAGGAGAGGAGCTTGAGCCAGCACCTTCCTGACAG

                                           [+1]
                                           1.6e-05
                                           AGCTGGGTGTGGCCGGGGGT
                                             +++++ +++++++++ ++
151  GGCTTTGGCGCTCCTTCCAAGAACAAGGCACAACCTAACAAAGGGAGTGGCCTCACTGTCCCGGTAGATTTAAGG


chr4:109112541-109113041
  LENGTH = 500  COMBINED P-VALUE = 2.02e-03  E-VALUE =      0.4
  DIAGRAM: 21-[-1]-13-[+1]-94-[+2]-302

                          [-1]                             [+1]
                          6.2e-05                          3.1e-05
                          ACCCCCGGCCACACCCAGCT             AGCTGGGTGTGGCCGGGGGT
                           + +++++ ++++++++                   ++++++ ++++ ++++
1    CCCATACAGCTCGGGGTCTGAGATCCCAGTCACACCCAATGGCCAGGCAGCTGGTAGTGGGTGAGGCTCCAGTCA

                       [+2]
                       7.7e-06
                       TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                       ++  ++  + +   ++++++++ +++++++
151  AATTAAGGGTTTGGGCTGTTTGTCTGTGCAAGTCCCTCTTTTCTCTGGGTGTTGGTCATGCCTGTGAAACTGGGA


chr3:97461668-97462168
  LENGTH = 500  COMBINED P-VALUE = 2.28e-03  E-VALUE =     0.46
  DIAGRAM: 18-[+2]-256-[-1]-81-[+1]-21-[+1]-34

                       [+2]
                       6.4e-05
                       TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                       +   ++++++ ++++++++ ++++ ++  +
1    CTGCCATCACGTGTCTAGTCAATTCTCTGTCCTACTTTTTATTTCATGCCTCCTGGGACAACTAAAAAGGTTGCT

         [-1]
         1.8e-05
         ACCCCCGGCCACACCCAGCT
          ++++ +++++++++++
301  TCCCGACCCGGACCCCACCCTCGGCCCCGCCCCAAGCCGGAGCTGCGCACGCACCCACCACAGAGGCGGTGCTGG

                                   [+1]                                     [+1]
                                   6.2e-05                                  4.4e
                                   AGCTGGGTGTGGCCGGGGGT                     AGCT
                                   +   +++ ++++++++++ +                      + +
376  TGGCTAGAGAGGCAGGCGACCCAGGCTGAGGAGGGGGCGGGGCTGGAGCGCAGGGGGCGGAACAAGAGGCTCGGT

     
     -06
     GGGTGTGGCCGGGGGT
     +++ ++++++ ++++
451  GGGCGGGGCCAGAGGCAGAGGCGGTACCTCGTCGCGGGCCTTGTAGCCAT


chr9:102674395-102674895
  LENGTH = 500  COMBINED P-VALUE = 2.38e-03  E-VALUE =     0.48
  DIAGRAM: 372-[+2]-98

                                                                             [+2
                                                                             2.5
                                                                             TTG
                                                                             ++
301  CAGGAATTAATTTTATTAACACTGAGATGATCCAAATGTGAATTGAGTGTGGCAGCCTGGGATTTATGGCATTTC

     ]
     e-06
     CTCCTCTCTTTTACCTCTTATCTCTGG
       ++++ ++++++++++++ + + +++
376  TGTCTGATCTTTTCTTCTTCTGTGTGGGTTCTTGTGAAATGTGTGTATATCCTTCCATATTTTTCTCTAAATCTC


chr17:24289205-24289705
  LENGTH = 500  COMBINED P-VALUE = 2.49e-03  E-VALUE =      0.5
  DIAGRAM: 262-[-1]-218

                                          [-1]
                                          7.5e-07
                                          ACCCCCGGCCACACCCAGCT
                                          +++++++ ++++++++++ +
226  CACTACAGTGACTCAGCTAACCTCAGGGAGTGGCTGTCCCCCAATCCACACCCATACCACAGGCACGTCTGATGC


chr17:28960252-28960752
  LENGTH = 500  COMBINED P-VALUE = 2.67e-03  E-VALUE =     0.53
  DIAGRAM: 221-[+1]-81-[+1]-158

                                                                            [+1]
                                                                            2.5e
                                                                            AGCT
                                                                              ++
151  GTGCTACTCTGCTCTGGGCTGCTGTAGTCCTAAGAGTCTGCGCTCTTCAACGCACTGGCTCTGTGAGGTAGCTCT

     
     -06
     GGGTGTGGCCGGGGGT
     +++++++++++    +
226  GGGTGTGGCTGACCCTAGGCCCTTATCCTGTCTTAGCTTCTGCTGCCATTGCCAGCTGGGTTGGAGAGGGCTTGA

                           [+1]
                           9.0e-05
                           AGCTGGGTGTGGCCGGGGGT
                           + +++ ++++++++
301  GAGTGGTTATCAGAAGAGGTAAGACTGTGTGTGGCTCTTCAAGAGGCAGAGGACCTCCCTGATAATTGAGGTTTG


chr2:73323093-73323593
  LENGTH = 500  COMBINED P-VALUE = 3.07e-03  E-VALUE =     0.61
  DIAGRAM: 49-[-2]-421

                                                      [-2]
                                                      2.4e-06
                                                      CCAGAGATAAGAGGTAAAAGAGAGGA
                                                      +++++   ++++ ++++++++++ ++
1    CCTTTCACCCCTTGTTGTTTTTCAGTCCAGACACGTTGGAAAACTAAAGCCAGACCCAAGACAGAAAGGAAACCG

     
     
     GCAA
     + ++
76   GAAACTGATCCTAGTCCCCTCTCTCCATCGCTATTTGTTTAGGTATTTGGNNNNNNNNNNNNNNNNNNNNNNNNN


chr11:32150818-32151318
  LENGTH = 500  COMBINED P-VALUE = 3.13e-03  E-VALUE =     0.63
  DIAGRAM: 151-[-1]-27-[-1]-118-[-2]-134

      [-1]                                           [-1]
      2.7e-05                                        3.1e-05
      ACCCCCGGCCACACCCAGCT                           ACCCCCGGCCACACCCAGCT
      +++  ++   ++++++++++                            ++ + +  +++++++++ +
151  CAAAGTAGCATACACCCATCTGGAACCTATCAGTGACCATAGTCAACAGCAGGTGTACACACCCAGGCCAAGGGT

                                         [-2]
                                         1.4e-05
                                         CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                         ++++++  +  ++++++++++++ +++  +
301  AGAGGCCACTAGGACTGCTGAGTAATACTTGGGGGTACAGAGTCAGAAAGGAAAGGACAAATGGTACCACTGATT


chr7:103853792-103854292
  LENGTH = 500  COMBINED P-VALUE = 3.29e-03  E-VALUE =     0.66
  DIAGRAM: 212-[-2]-42-[+1]-196

                                                                   [-2]
                                                                   1.8e-05
                                                                   CCAGAGATAAGAG
                                                                   ++++++ ++  ++
151  ACCATTGAAGAGCTACATATCAATATTTGTAGGCCACAGCTAGGTTGTAAGCCACAGTGATGCCAGAGCTATTAG

                                                                [+1]
                                                                2.3e-05
     GTAAAAGAGAGGAGCAA                                          AGCTGGGTGTGGCCGG
     ++++ ++  + ++  ++                                          + +++++ +++++  +
226  AAAGTGGTTACAAAGAACTGCTCAGGAAAATCTGATGGCTTCAACTTAACTAAATGACAGTATGGGCGTGGCAAG

     
     
     GGGT
     +  +
301  AAAGGAGGTGGATGTAAGATAACGTTAGGAGAATTTATGACTCCAATTAGAGGAAGTCAGTCCACTAGTAGCATG


chr16:49839621-49840121
  LENGTH = 500  COMBINED P-VALUE = 3.53e-03  E-VALUE =     0.71
  DIAGRAM: 192-[+2]-47-[-1]-17-[+2]-164

                                               [+2]
                                               5.9e-05
                                               TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                               ++  ++  + +++  ++++++  ++ ++++
151  TCAGGGAATGCTGTAACCTTCCGAACTTAGCACAAAGGTGGCTTTTTTTCCACCCGGCTTTCTCTTCACTGGTTT

                                                 [-1]
                                                 7.7e-06
                                                 ACCCCCGGCCACACCCAGCT
                                                   +   ++ +++++++++++
226  TATGAGCCGGTGCCAGCTGAGTCTAGATGGTAGAGTTTTACACTTGAATGAAACACACCCTGCCCTCGGTTCTGG

           [+2]
           9.6e-05
           TTGCTCCTCTCTTTTACCTCTTATCTCTGG
               ++  + ++++ ++++  ++ +++++
301  GAGCTCCACTCTGCTGCCTCCATCTGCTACCTCTGATAAATGCTCATATTTTAAATATGTTACAATCAGCATACG


chr6:135115628-135116128
  LENGTH = 500  COMBINED P-VALUE = 3.67e-03  E-VALUE =     0.73
  DIAGRAM: 231-[-1]-249

           [-1]
           7.0e-07
           ACCCCCGGCCACACCCAGCT
             ++++++ ++++++++ ++
226  CAAGCATTCTCAAGACCCACCCAACTAAGCACAGAGGGCTCCCCATCCCTCCCTCCCTGAGCAATGAAGAGCCTG


chr3:88305500-88306000
  LENGTH = 500  COMBINED P-VALUE = 3.83e-03  E-VALUE =     0.77
  DIAGRAM: 229-[+1]-251

         [+1]
         3.4e-06
         AGCTGGGTGTGGCCGGGGGT
           +++++ +++++++++++
226  NNTGCAATGGGAGTGGCCTGAGGCTCCCTAACGGCTGGATTTCAAAAATGTCATTGTATTCCAGAGGTTTAGTAA


chr18:57137388-57137888
  LENGTH = 500  COMBINED P-VALUE = 3.89e-03  E-VALUE =     0.78
  DIAGRAM: 296-[+2]-174

                                                                            [+2]
                                                                            1.6e
                                                                            TTGC
                                                                            ++
226  AATGACTTAGAGTCAGCCCTTCCATTTATGGCCTCAGAGGGGCTAGACGTGTGGGTGTGAGAGGCAGTAGATTCA

     
     -06
     TCCTCTCTTTTACCTCTTATCTCTGG
     ++++++++++++  + ++ ++++++
301  TTCTTTCCCCTTGGCTTTGTCTCTGAGAAAAGCAGAAGTAAAGAAATGGCTGTTGGTACAAAAGTGTTTCCTTCA


chr5:97380648-97381148
  LENGTH = 500  COMBINED P-VALUE = 4.16e-03  E-VALUE =     0.83
  DIAGRAM: 188-[-2]-282

                                           [-2]
                                           1.6e-06
                                           CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                             +++++ +++++ ++++++++++++
151  GAAAGTTTCCTAGAAGAGGGGCCCATAAACCGAATCTTTAAGAGAAAAGAGTTAAGGGAGAGGGCGGGAGGGGGT


chr15:91082416-91082916
  LENGTH = 500  COMBINED P-VALUE = 4.40e-03  E-VALUE =     0.88
  DIAGRAM: 239-[-1]-104-[-1]-73-[+2]-14

                   [-1]
                   7.7e-06
                   ACCCCCGGCCACACCCAGCT
                   +++ +  ++++++++++ ++
226  AGCCTTTCAGAGATAAAAGGCACCACACCCTCCCAGCAGAGACATCTGTAGCCATAGTCTCTTATCAGGCTTTAT

                                                                    [-1]
                                                                    4.1e-05
                                                                    ACCCCCGGCCAC
                                                                    ++++ +++  ++
301  TTATAAGAACCCGGAGTAGAACAACAAAATAAACCCAGTTGTTTAACCTCACTAACTTCCTAGAAATTAAGAAAC

     
     
     ACCCAGCT
     ++++++ +
376  ACCCTGGTTTTAAAAAACGATAAAGGAAACAAAAATCATTAATTACATAGAAAAGTAGTAAATTTACACCAATTG

           [+2]
           7.7e-05
           TTGCTCCTCTCTTTTACCTCTTATCTCTGG
            ++ ++ ++ +++  + ++++ + +++++
451  TGTGTTCTGAAGGTGATTTACAATCCTAAGCTCTGACTGTATCTTTAAAA


chr14:61272713-61273213
  LENGTH = 500  COMBINED P-VALUE = 4.55e-03  E-VALUE =     0.91
  DIAGRAM: 216-[+2]-104-[+1]-130

                                                                       [+2]
                                                                       1.1e-05
                                                                       TTGCTCCTC
                                                                           +++++
151  AATTAAGAGTCTGAAACAGTCCTCTGGAACTGCAGTGTACACAGGTTCTCACGCTCAGCTGCGGGACACTATCTG

     
     
     TCTTTTACCTCTTATCTCTGG
     +++++ +++++ + + +++ +
226  CCCCCCTCCTCATCTGTCTCCTGGAGATAAGTCCAAGCCTCTTAGCATCCTTCTGAGAACCCAGAGAGACTCAGG

                                                       [+1]
                                                       5.4e-05
                                                       AGCTGGGTGTGGCCGGGGGT
                                                          ++++++++ +++   +
301  TGACAGGCCTTCAACACAGCACACGGCCTGGCAGGGCTGATAAGGAGGAGCAGTGGGTGTGTCCTTCATCTTTCC


chr5:33616214-33616714
  LENGTH = 500  COMBINED P-VALUE = 4.65e-03  E-VALUE =     0.93
  DIAGRAM: 247-[-1]-233

                           [-1]
                           3.6e-06
                           ACCCCCGGCCACACCCAGCT
                             ++++ +++++++++++
226  ATGAAGGCAGGCCTGGAGGGCCTTACCCCGCCACACCCTGAAACAAACTGACAGGATCTGCAAAATGGCCTTGTG


chr18:23982470-23982970
  LENGTH = 500  COMBINED P-VALUE = 4.86e-03  E-VALUE =     0.97
  DIAGRAM: 285-[-1]-195

                                                                 [-1]
                                                                 6.5e-06
                                                                 ACCCCCGGCCACACC
                                                                  ++ ++ +++++ ++
226  NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAAAGCCACCACGCC

     
     
     CAGCT
     +++++
301  CAGCTGACTAAGCATCTTAATCCTTGGACATAGATGTACTTTTTTAAAAAAAGAATATTTATGGTTGAAGTTATT


chr9:24715045-24715545
  LENGTH = 500  COMBINED P-VALUE = 4.96e-03  E-VALUE =     0.99
  DIAGRAM: 214-[-1]-153-[+1]-93

                                                                     [-1]
                                                                     5.8e-06
                                                                     ACCCCCGGCCA
                                                                     +   ++++ ++
151  GGGGGTATGGCAACAGGAGGAGTGTGTGAGGATTTATTCCCATTTTCTGACCCGTGTATTTCTAAGGAGAAGGCA

     
     
     CACCCAGCT
     + +++++++
226  CGCCCTGCTTATGCAGACTGCACCCCACTATCTGTCTGTTACCCTCTTCATAAGGCCAGCACCGAGCAGGTGGAG

                 [+1]
                 2.7e-05
                 AGCTGGGTGTGGCCGGGGGT
                   +++++ ++++++ + +++
376  GTGGAGGAGACACACAGGGAGGGGCCACTGTGTTGTTAGGCAACAGAACCCAAAGTCCTGAATAACATGAGACAG


chr10:116195445-116195945
  LENGTH = 500  COMBINED P-VALUE = 5.44e-03  E-VALUE =      1.1
  DIAGRAM: 400-[+2]-70

                              [+2]
                              5.9e-06
                              TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                              ++ ++  ++ + +++++++++ + +++++
376  ACAGTTGAGATGGGGGGCCCAAGATTTCCCATTCACACTTTTCCCTGACCTCTGAAAATAACGGGAAATGGGCTT


chr11:77795184-77795684
  LENGTH = 500  COMBINED P-VALUE = 5.78e-03  E-VALUE =      1.2
  DIAGRAM: 247-[+1]-42-[-2]-67-[-2]-64

                           [+1]
                           2.4e-05
                           AGCTGGGTGTGGCCGGGGGT
                           +++++++ ++ +++ ++ ++
226  TTGAAGTCAGCTGTAGGCAGGTAGCTGGGCGTTGTCAGGATTACGGACTGTTTGGGCTTTTGACTTCCTCTTTCG

              [-2]
              6.9e-05
              CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
              ++++ ++ +  ++ ++++++++ + +  ++
301  GAGTAGTTCACAGGGACAGTGGTTAAGAGAGGGTAAGAACAGCTTGAAATATCTTGGGTTCCATCGGGACCCAAG

                                    [-2]
                                    3.4e-05
                                    CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                    + ++ +  ++ ++++++++++++++++ ++
376  GCAGCAATGCTCGTGCTAAAATTAGGTGCTGAGAGTGGAAATGAAGTGGAAAGAGCAGTCATCCGATCTGCCACC


chr16:32508975-32509475
  LENGTH = 500  COMBINED P-VALUE = 6.57e-03  E-VALUE =      1.3
  DIAGRAM: 213-[+2]-29-[-1]-208

                                                                    [+2]
                                                                    1.3e-05
                                                                    TTGCTCCTCTCT
                                                                      + ++++++ +
151  GCCCACCCCTTCTCCGAGGGCCCTTTGTCCTTCCCTAGATCTCAGGCGAGGCTGGCAGGGCTTCAGTTGCTCTGC

                                                    [-1]
                                                    7.3e-05
     TTTACCTCTTATCTCTGG                             ACCCCCGGCCACACCCAGCT
     ++ + ++ +   ++++++                             ++  +  +++++ +++++ +
226  TCCCACTTTCTCCTCTGCCCCTTTTTGCAGAACCTACCTTTGCTTCTCAGACTTACCCCGCCCAGTCTTTGGCTG


chr18:80416880-80417380
  LENGTH = 500  COMBINED P-VALUE = 7.26e-03  E-VALUE =      1.5
  DIAGRAM: 239-[-1]-241

                   [-1]
                   1.8e-06
                   ACCCCCGGCCACACCCAGCT
                   +   + ++ ++++++++ ++
226  GAGGGCCTCTCACCCTTGGGAGACACACCCACCTTATCTCCTCTGAGTGCTCTGGCCTGNNNNNNNNNNNNNNNN


chr10:57252236-57252736
  LENGTH = 500  COMBINED P-VALUE = 8.25e-03  E-VALUE =      1.6
  DIAGRAM: 155-[+1]-158-[+2]-137

          [+1]
          1.5e-05
          AGCTGGGTGTGGCCGGGGGT
          +++++++ +++++++   +
151  CGAGAGGAAGGGCGTGGTCTTCAGCGATGCTAGATTTGTGGCTTCATGGAGTGGGCCTACTTTGCCAAGTAAAGA

                                      [+2]
                                      8.0e-05
                                      TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                        + +++ +++++  ++++ ++ +++ +++
301  TCCTCTTGGGATTTAGCCATCTCATTTCCACTAAAGTCCCCTTTTTAGTTTTGTTTTCTTTGTTGTTGTTCTACT


chr5:34915767-34916267
  LENGTH = 500  COMBINED P-VALUE = 8.43e-03  E-VALUE =      1.7
  DIAGRAM: 179-[+2]-29-[-1]-242

                                  [+2]
                                  3.9e-05
                                  TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                  ++ ++++ + +    +++++ + +++ +++
151  TGAAGAGGCCTCGGTGTTTGTTAATCCACTGTCATCCGGCGGGCCCTTCCTGTCTGTGGAGCTTTATCAGAGCAC

                  [-1]
                  3.1e-05
                  ACCCCCGGCCACACCCAGCT
                  +  ++ +++ ++++++++ +
226  ACACAGACATCTCAGTCCTGACTCCACCCTGATTGACAGCCCAGTCTCCCAAACTGCCTACTGATCTTCTCGCCT


chr9:98389943-98390443
  LENGTH = 500  COMBINED P-VALUE = 8.52e-03  E-VALUE =      1.7
  DIAGRAM: 252-[-1]-228

                                [-1]
                                1.1e-05
                                ACCCCCGGCCACACCCAGCT
                                + ++ +++++++++++  ++
226  TGCTCACCACAATTAATAGCCCTTCTTATCTTCAGCCCCACCCCACCAGGCCAGCTTGCCTTATATTCTTGCATG


chr19:5845899-5846399
  LENGTH = 500  COMBINED P-VALUE = 8.66e-03  E-VALUE =      1.7
  DIAGRAM: 136-[+1]-193-[+1]-131

                                                                  [+1]
                                                                  1.6e-06
                                                                  AGCTGGGTGTGGCC
                                                                  ++++++++++++ +
76   GGCGCGTGACTTCTCGGGCGTTGCCGCCGCCTGCTCGCAGGGTGACGTCAGTGCGGGCAGCAGCAGGGTGGGGGT

     
     
     GGGGGT
     ++++
151  GGGGAAGAACTATCCCAGCAGCTTGGGTGGAATGCTTAATTGCGTCTAAGGTTAATTAAATTGCGGGAAAGGTGG

                                                      [+1]
                                                      2.4e-05
                                                      AGCTGGGTGTGGCCGGGGGT
                                                         ++++++++++ + +++
301  GGTTGAAGAGCGCCCAGTACAGTTAAGTGATTTTAGAAAACATTTTTGCTTTTGGGTGTGGTATAGTGAGAAAAA


chr3:151777796-151778296
  LENGTH = 500  COMBINED P-VALUE = 1.11e-02  E-VALUE =      2.2
  DIAGRAM: 30-[-2]-58-[-1]-362

                                   [-2]
                                   2.5e-05
                                   CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                   +++++++  +  +++ ++++ +  ++  ++
1    GGTAAAGACGCGAGATGACCACAGCCAACGGCAGAGAGGACTGAACAGAGCAGAGGAGAAACCGGTCCAGCCCAT

                                                [-1]
                                                6.7e-05
                                                ACCCCCGGCCACACCCAGCT
                                                   + +++ +++ +++++++
76   GAGTTCTGCAAAGTCAAAGACTTCAGAAGCAAGGAGAGGGCAGTTGCACAGTCCCGCCCAGCCGGGTGACTCTGC


chr4:76585120-76585620
  LENGTH = 500  COMBINED P-VALUE = 1.12e-02  E-VALUE =      2.2
  DIAGRAM: 329-[+2]-141

                                  [+2]
                                  2.5e-06
                                  TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                  ++  ++  +++++++++++ ++++ +++++
301  TTGTTGTCTTCTCCTCCTTTTAACCTAAGTTCTCCTCCCCCTCTTCCCTTTATTTCTGCAATTCCTCCTCCTGCT


chr7:104332488-104332988
  LENGTH = 500  COMBINED P-VALUE = 1.12e-02  E-VALUE =      2.2
  DIAGRAM: 164-[+2]-23-[-1]-222-[+1]-21

                   [+2]                                                 [-1]
                   6.6e-05                                              2.6e-05
                   TTGCTCCTCTCTTTTACCTCTTATCTCTGG                       ACCCCCGG
                   +  +++   ++++ ++ ++++  + +++++                       + ++++ +
151  CAACATGGTCTTTCTATCATTCATCTTATCATTCTGCTGTCTGTCTGAAGCAAGTTGTCTTTGGCTTATCTGCTG

     
     
     CCACACCCAGCT
     ++++ +++ +++
226  CCACTCCCCTCCTGCTGCTGTGTTAGTTCCCACTCTTGTGACCATAAGCCTCATAAGTGCTCTTTTAACCACCAT

              [+1]
              9.4e-05
              AGCTGGGTGTGGCCGGGGGT
               + + ++ ++++++++ +
451  TTTAAAAAATGTATGGCGTGGCCTCTTCCCACCAGCAACTGCAGTGTAGT


chr5:138127197-138127697
  LENGTH = 500  COMBINED P-VALUE = 1.23e-02  E-VALUE =      2.5
  DIAGRAM: 238-[+1]-242

                  [+1]
                  4.6e-06
                  AGCTGGGTGTGGCCGGGGGT
                    ++++++++++++++   +
226  GTCTGTCTTTTGCTACAGGGTGTGGTCTGCAAGAGCAACCAGAGGGTGCGCTTCCTCCTCCTGTCTCTACTCCAC


chr11:60988820-60989320
  LENGTH = 500  COMBINED P-VALUE = 1.26e-02  E-VALUE =      2.5
  DIAGRAM: 115-[+1]-68-[+1]-47-[+1]-210

                                             [+1]
                                             9.5e-06
                                             AGCTGGGTGTGGCCGGGGGT
                                             +++ +++++++++ ++++ +
76   TTGCACCGGCCTGAGCTCTGCCGCAAAGAGGCGGGGCGACGGAGGGGTGGGGCAGGGTAGGGCCTGCGTCTGCGA

                                                          [+1]
                                                          8.3e-05
                                                          AGCTGGGTGTGGCCGGGGGT
                                                          +  ++++ ++  ++++++ +
151  GTTCTCTGAAAGGAGGGTTTCTAGGTTCTGTTTGTTGGTCCTTGGAGTTCCTAGTGTGGGCGTTTCTGCAGAGAC

                                                  [+1]
                                                  8.0e-05
                                                  AGCTGGGTGTGGCCGGGGGT
                                                  +  ++++ +++++  ++ +
226  TGCCATCTTGGCGACTGTGTTGGGTACCGCAATGCCACAGCTGGAGATTGGGCGTGGCAAGAATACAGATCTTCC


chr8:19984030-19984530
  LENGTH = 500  COMBINED P-VALUE = 1.29e-02  E-VALUE =      2.6
  DIAGRAM: 103-[-1]-81-[+2]-266

                                 [-1]
                                 3.3e-05
                                 ACCCCCGGCCACACCCAGCT
                                  +++  +  +++++++++ +
76   TTTTATTGAAAAAAAAAAAATCACCTCTTCCTTTGTACACACCCAGGCTCACAACACCCACTTTCTCCTCCTGAA

                                                           [+2]
                                                           6.2e-05
                                                           TTGCTCCTCTCTTTTACCTCT
                                                            ++ +   ++++++ + ++++
151  AGGGTTTTGGTTTTTTCATGTCCTGATGGAGTGAGGCCCTGGAGCATCCCAGTCCTGAAATCCTTTCTGAACTCT

     
     
     TATCTCTGG
     + +++ + +
226  TGTCTGTCCCCAGCAGGAGCTATCTGCCATAATCACTTTGAGCCCATGTCAAGACCTTGAACATAAAGTCTAGGA


chr11:31712262-31712762
  LENGTH = 500  COMBINED P-VALUE = 1.45e-02  E-VALUE =      2.9
  DIAGRAM: 118-[+2]-53-[+2]-269

                                                [+2]
                                                3.9e-05
                                                TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                                                  + +++++  ++   +++++++++++ ++
76   GTCCCTGCGGTCAGGCCCTGCAAAGAACGCAGGTTTGTTTTCTCCGGAGCTGAGCCGGGTCCCTTATCTCAGGCA

                                                        [+2]
                                                        1.2e-05
                                                        TTGCTCCTCTCTTTTACCTCTTAT
                                                        ++  ++  ++++++ ++++++ +
151  CTCAGACCATCACGTGATCTGGCAAGCTGCACACAGGCTTTAGGGAAGTCTTTTTCTGACCTCCCCACCTCTGAC

     
     
     CTCTGG
     +++ ++
226  CTCAGTCTCTGGTTCCTGTTGCTTCGAGACTGCATGGTTACCTTTTTATCCCCACAGACCATGGAGCACCTGTTA


chr15:41338514-41339014
  LENGTH = 500  COMBINED P-VALUE = 1.48e-02  E-VALUE =        3
  DIAGRAM: 173-[+2]-75-[+2]-192

                            [+2]
                            4.1e-05
                            TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                             +  ++ ++ + +  ++++++  +++ +++
151  CAGGCTACCTCTCATAAGCTGTTGGCATTGTCACATGGCCCTCTGTTCTTTGGCCACTCCTACTTTCATGTTAGN

                                                          [+2]
                                                          8.7e-06
                                                          TTGCTCCTCTCTTTTACCTCTT
                                                          ++ ++++++ +++++++++ +
226  NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCACATTTACTGCTGACCTTTTTCCTTA

     
     
     ATCTCTGG
     + ++ +++
301  AGCTGTGTACGTGCCCTCCAGTTCACCCTCCAACTTGAAGAAAGACAGCGCGTGTTTGATCTTACCATCNNNNNN


chr9:21362671-21363171
  LENGTH = 500  COMBINED P-VALUE = 1.49e-02  E-VALUE =        3
  DIAGRAM: 105-[+1]-131-[+1]-224

                                   [+1]
                                   4.7e-05
                                   AGCTGGGTGTGGCCGGGGGT
                                    + ++++++++ + + ++ +
76   CAGCTCTTCCATACCCACTGGGAAGAGTTCTGTTGGGTGTGCTGTTGGCTCTGGGAGAAGCGTGCGTGGAGGAGC

                                    [+1]
                                    1.1e-05
                                    AGCTGGGTGTGGCCGGGGGT
                                    ++ ++++++++ + +   +
226  TCTATGTACAGGGTAGCAATTCCACCAACTCAGGAGGGTGTGTCAGACCTATCTTCCCTGTGCACTGTGACCTTC


chr18:58822702-58823202
  LENGTH = 500  COMBINED P-VALUE = 1.52e-02  E-VALUE =        3
  DIAGRAM: 467-[-2]-3

                      [-2]
                      2.1e-05
                      CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                      + +++ + + +++++++ +++++ +++++
451  TCCAGACTATTGGTTTGATAGACAGAGGAGATTATGGGAAACTGCAGTTA


chr1:173447614-173448114
  LENGTH = 500  COMBINED P-VALUE = 1.68e-02  E-VALUE =      3.4
  DIAGRAM: 369-[-1]-111

                                                                          [-1]
                                                                          3.9e-0
                                                                          ACCCCC
                                                                          +   ++
301  TGGGGATGGGAATAGGTAAGGGTTTCTCAGTGTGTCTGATATTTAATTCCAAGAACCGGAATTAAAGGCATGAGC

     
     6
     GGCCACACCCAGCT
     ++++++ ++++ ++
376  AGCCACTCCCACCCAGCACATAATTCTGTGACACACAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCA


chr6:81915769-81916269
  LENGTH = 500  COMBINED P-VALUE = 1.74e-02  E-VALUE =      3.5
  DIAGRAM: 197-[+1]-283

                                                    [+1]
                                                    8.1e-06
                                                    AGCTGGGTGTGGCCGGGGGT
                                                    +   +++++++++++++ ++
151  CATGTCTACACCCTCAATGAAGGACTACAACTCCCAGAAGTCAGTGCGATGGGGTGTGGCCGGACGGTGGCTCCT


chr1:169322898-169323398
  LENGTH = 500  COMBINED P-VALUE = 1.93e-02  E-VALUE =      3.9
  DIAGRAM: 253-[-1]-227

                                 [-1]
                                 2.1e-05
                                 ACCCCCGGCCACACCCAGCT
                                   + +  +++++++++++
226  CAGTGTCTCTTACTCCCTTCCACCACCCTGCAGGTGCCCCACCCTGTGGTTCTGGGTCTCCCTGTAGCGACACAA


chr12:70860461-70860961
  LENGTH = 500  COMBINED P-VALUE = 1.94e-02  E-VALUE =      3.9
  DIAGRAM: 197-[+2]-22-[-1]-231

                                                    [+2]
                                                    4.9e-05
                                                    TTGCTCCTCTCTTTTACCTCTTATCTCT
                                                      + +++ + +++ ++ +++ ++++++
151  NNNNNNNNNNNNNNNNNNNNNNNNAGTCCAGCTGTGGCAAAAAGGACCAGACGCCCATTTAACACTCCTATCTCA

                             [-1]
                             6.7e-05
     GG                      ACCCCCGGCCACACCCAGCT
      +                       +++  +++ ++++++++
226  CCAGGGCAGACACTAGGACTTGGCGCCTAGGACTCCACCCATTGTAACTGCAGCAAGCATCTGGAGTTACCTCTT


chr9:59598186-59598686
  LENGTH = 500  COMBINED P-VALUE = 1.96e-02  E-VALUE =      3.9
  DIAGRAM: 163-[-2]-10-[-1]-277

                  [-2]                                    [-1]
                  4.6e-05                                 7.3e-05
                  CCAGAGATAAGAGGTAAAAGAGAGGAGCAA          ACCCCCGGCCACACCCAGCT
                  ++ ++++ ++    +++ +++++++++ +            +++++++++ ++++ + ++
151  ACTGCTTCCAAAAACTGAGACAAACCTAAGTAGGGAGGAGGCGTCTTACCTATTCCTCAGGCCTCACCAACCCAA


chr3:19550495-19550995
  LENGTH = 500  COMBINED P-VALUE = 1.98e-02  E-VALUE =        4
  DIAGRAM: 452-[-2]-18

       [-2]
       1.1e-05
       CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
        ++++ + ++++++++++++++  ++  +
451  ATTCAGAAAAAAGAGAAAAGAAAAGCAAAGCCTTGAATTCTGGGGCAGAC


chr7:36132953-36133453
  LENGTH = 500  COMBINED P-VALUE = 2.01e-02  E-VALUE =        4
  DIAGRAM: 157-[-1]-323

            [-1]
            2.5e-05
            ACCCCCGGCCACACCCAGCT
            + +++ ++ +++ +++++
151  ACTCCGCCTACCGGGACACTCCCAGGGAGTAGCCACTGGCCCTGAAGATAAGCCTCACCAAGGAATTCATTCAGA


chr7:38970375-38970875
  LENGTH = 500  COMBINED P-VALUE = 2.06e-02  E-VALUE =      4.1
  DIAGRAM: 49-[+1]-114-[+1]-297

                                                      [+1]
                                                      4.9e-05
                                                      AGCTGGGTGTGGCCGGGGGT
                                                      + +++++ +++++ + + ++
1    GCCCCCTGACACTTGCTAAGGAGCCTGGCTTGTCTTCTGGCAAAGGCTTGTCTGGGCGTGGTAGAGATTGAGAAT

                                      [+1]
                                      1.6e-05
                                      AGCTGGGTGTGGCCGGGGGT
                                      +++++++++ + ++ +   +
151  GTAGATAATTCTTTGAGTAGGTAATCAGGGGTAAGATGGGTGAGTCCAGTACTCATTCCCAGCTCCCTCCCNNNN


chr15:78243390-78243890
  LENGTH = 500  COMBINED P-VALUE = 2.19e-02  E-VALUE =      4.4
  DIAGRAM: 234-[+1]-246

              [+1]
              3.1e-05
              AGCTGGGTGTGGCCGGGGGT
                 ++++++++ +++++  +
226  GTACAGTGACTTTGGGTGTGACTTCGCCTTAGGCTGGCCATCTGTGTGTGGGGCGGTGCCTAACTCTGCTGGCTG


chr7:87847381-87847881
  LENGTH = 500  COMBINED P-VALUE = 2.20e-02  E-VALUE =      4.4
  DIAGRAM: 99-[+2]-2-[-1]-230-[-1]-99

                             [+2]                            [-1]
                             7.4e-05                         5.2e-05
                             TTGCTCCTCTCTTTTACCTCTTATCTCTGG  ACCCCCGGCCACACCCAGC
                             +   +++++++ +  + +++++ ++++  +   ++   ++ +++++++++
76   TGGCTGCTCAGTCTTCGTGGCTGCTCTGTCCTCCTGTGGAGCTCTTCTCTCACTGTGCCATGGATCACACCCAGG

     
     
     T
     
151  GCCTCACAGGGGTAAGTGGCTGCTCTTCCACTGACGTCCACAAGGCTGCAACTCTCCTGGGAAACTTCATGACGA

           [-1]
           7.0e-05
           ACCCCCGGCCACACCCAGCT
           +  ++ ++  +++++++ +
376  GATTCTATGTCGAGGTCCACCCACCATCAGATATGTGTGAAGAAAAGAACCTAATCACAGAATTCATAGAGAGGG


chr1:33631214-33631714
  LENGTH = 500  COMBINED P-VALUE = 2.21e-02  E-VALUE =      4.4
  DIAGRAM: 358-[-1]-122

                                                               [-1]
                                                               3.4e-06
                                                               ACCCCCGGCCACACCCA
                                                               +  +  ++++++ ++++
301  NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCTGCTTTGCTGCTGGGCCACGCCCT

     
     
     GCT
     ++
376  GCGACCCACGGGTTGAAAGTCACTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN


chr4:135407873-135408373
  LENGTH = 500  COMBINED P-VALUE = 2.25e-02  E-VALUE =      4.5
  DIAGRAM: 116-[-1]-64-[+2]-270

                                              [-1]
                                              9.0e-05
                                              ACCCCCGGCCACACCCAGCT
                                                ++++++ ++++ ++++++
76   NNNNNNNNNNNNNNNNNNNNNNNNNNCAGGCAAGGGAAGAGGGATCCGAACCCAGCCAGCTTACTGCTTGCTGCT

                                                       [+2]
                                                       4.4e-05
                                                       TTGCTCCTCTCTTTTACCTCTTATC
                                                       ++ +++ ++  +  +++++  ++ +
151  CGGGCATGAGGACCTGGGCCACGCCTGTAAGCCCAGCAGAGACAGATCCCTGCCAGTTTGGCAGAATCTGATAGC

     
     
     TCTGG
     +++++
226  TCTGGGTTCTATGGGCGGAACCCTCTGGAGACATGCTGTACTTTCAGATATGTTTGCTCCTAACGTAGCTAACGG


chr7:101244829-101245329
  LENGTH = 500  COMBINED P-VALUE = 2.27e-02  E-VALUE =      4.5
  DIAGRAM: 311-[-2]-159

                [-2]
                1.0e-05
                CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                 ++ +++  +++++++ +++ +  ++  ++
301  ATTTTGAGTTTTCAAAGAGGAGAGGTTCAGACATAGATTCAAAGTATGAAATAAAGCAGAGAAGTCCCTTAGCAC


chr10:60612190-60612690
  LENGTH = 500  COMBINED P-VALUE = 2.35e-02  E-VALUE =      4.7
  DIAGRAM: 215-[+1]-265

                                                                      [+1]
                                                                      8.5e-06
                                                                      AGCTGGGTGT
                                                                      +  +++++++
151  GCAGGTGACAGCACAGTGACAGCAGTGACAGCCAACTTTGCCCCCTTGTGAATGCTGATACTCAAATGAGGGTGT

     
     
     GGCCGGGGGT
     ++++ +   +
226  GGTTAGCAATGGCATTCTTATCTCCACCTAGTGTGTCCGAGATGGGACATTTTACCTCCTCTGCATCCCGTGACA


chr19:56465963-56466463
  LENGTH = 500  COMBINED P-VALUE = 2.40e-02  E-VALUE =      4.8
  DIAGRAM: 306-[+1]-36-[+1]-18-[+1]-80

           [+1]                                                    [+1]
           3.6e-05                                                 3.3e-05
           AGCTGGGTGTGGCCGGGGGT                                    AGCTGGGTGTGGC
           ++++++++++++    ++                                      +   +++++++++
301  AGATAAGGCTGGGTGTGGGGAAGTCAGCCAGAGCGGAGGAAGCTGCATAGCAAGAAGCAGAGACTGGGGTGGGGC

                              [+1]
                              1.9e-05
     CGGGGGT                  AGCTGGGTGTGGCCGGGGGT
     + +++                    +   ++++++++++ ++++
376  TAGGGCAGTGTCTCACTAAGCAGAGGTTGGGGTGGGGCCAGAGGCTGCCCTCTCCTTGCTCAGAGGGACTCAAAG


chr4:41334759-41335259
  LENGTH = 500  COMBINED P-VALUE = 2.43e-02  E-VALUE =      4.9
  DIAGRAM: 204-[+1]-276

                                                           [+1]
                                                           3.4e-05
                                                           AGCTGGGTGTGGCCGGGGGT
                                                           +++++++ +++ + +  +++
151  CTGGGTTGAGTCAGCTGTGACAGTACCTCCTTTGGGATGTGGCTGCTCATTTCTAGAAGGGCGTGCCGGTTTGTT


chr8:92969521-92970021
  LENGTH = 500  COMBINED P-VALUE = 2.59e-02  E-VALUE =      5.2
  DIAGRAM: 453-[+2]-17

        [+2]
        4.9e-06
        TTGCTCCTCTCTTTTACCTCTTATCTCTGG
        +++ ++  +++ ++ +++ ++  +++++++
451  CAATGGACTTAGCCATCCTCCACTGCTCTCTGTGAGAGACCAGGGCAGGT


chr6:145703215-145703715
  LENGTH = 500  COMBINED P-VALUE = 2.64e-02  E-VALUE =      5.3
  DIAGRAM: 154-[-2]-58-[+2]-228

         [-2]
         5.5e-05
         CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
         + +++ +++  ++++++++ ++++++   +
151  TGTTGGAGATATAGCAGAGAAAATGCAGAGAGTACCTGTTGCTGTGGACTAGTGGGGGAGGTGGGTGGTCAAGGA

                      [+2]
                      1.8e-05
                      TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                      ++ +++  + +++++ ++++++ +++ +++
226  GGGAGTCTTTCTACATGTTTCTGAGTGTTTTAGCCTCTTCTCTTTGTAGGCAGTAGGTTGCCCGTGGGCTCTCTG


chr13:57679178-57679678
  LENGTH = 500  COMBINED P-VALUE = 2.76e-02  E-VALUE =      5.5
  DIAGRAM: 217-[-1]-263

                                                                        [-1]
                                                                        1.9e-05
                                                                        ACCCCCGG
                                                                          +   ++
151  GCTGCCAACTACTATTGACTACTGTTGTCGCCTTCTCCAGCTTCTATCTTTCAGCTCCAGCTGCATCTGCAAGAG

     
     
     CCACACCCAGCT
      +++ +++++++
226  TCACGCCCTTCTTAGAACTGCAGCTGTGTGTAGTGGGACTGTTCACTTTCTCAGTAAGAGTGAGGCACCTGTGAC


chr19:45121628-45122128
  LENGTH = 500  COMBINED P-VALUE = 2.78e-02  E-VALUE =      5.6
  DIAGRAM: 35-[-2]-435

                                        [-2]
                                        2.6e-05
                                        CCAGAGATAAGAGGTAAAAGAGAGGAGCAA
                                        ++++++++ + ++++++    +  ++  ++
1    AGAAGAATCTTTCTGATGCGCCTGCTTGGATGCAGGCAGAGATCACGGGAAACTTTGGCCGTGCACATCCCTAGG


chr15:79757891-79758391
  LENGTH = 500  COMBINED P-VALUE = 2.80e-02  E-VALUE =      5.6
  DIAGRAM: 310-[+1]-170

               [+1]
               4.5e-05
               AGCTGGGTGTGGCCGGGGGT
               + +++++ ++ ++  ++ ++
301  CTGGAAACCTATCTGGGCGGAGCACGACGGCCTGCTGGAGATAAACACGACCACGTGACCGTAGCCCCGCCCCCG


chr1:134264178-134264678
  LENGTH = 500  COMBINED P-VALUE = 2.83e-02  E-VALUE =      5.7
  DIAGRAM: 23-[+2]-447

                            [+2]
                            3.5e-05
                            TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                             + ++++++++++++ ++++ ++ + ++++
1    GCTCCCTCCTGGCTTCTGCTTCCCGCCCTCTGCTTTCTGTCCCCTAGCACTGCCCAGACAGACACCACCCAAGAG


chr13:81067500-81068000
  LENGTH = 500  COMBINED P-VALUE = 3.19e-02  E-VALUE =      6.4
  DIAGRAM: 252-[+1]-228

                                [+1]
                                2.6e-05
                                AGCTGGGTGTGGCCGGGGGT
                                  +++++ +++++ ++++++
226  GTGGTAGAAACTGCACTAATATTTACATAAAGGGCGTGGTGGGGTGGGGTAGCAGCAAAGCCTGACTGAAGTGGG


chr11:69714224-69714724
  LENGTH = 500  COMBINED P-VALUE = 3.21e-02  E-VALUE =      6.4
  DIAGRAM: 145-[+2]-325

                                                                           [+2]
                                                                           5.5e-
                                                                           TTGCT
                                                                              +
76   CTGCACATAGCCCTGCCCGTTGGCCCTGCCCCCATCGCGGCGGGCGGTGGGCGCTGGGGGCTCCGGGTCAGACCG

     
     05
     CCTCTCTTTTACCTCTTATCTCTGG
     +  +++++++ ++++++ ++ ++++
151  GACCTCCTCTGCCTCTTCTCCCTGGCGCTGAGGCAGGTGAAAGGTCGACTATCAGACTTCAGCCTGGGAGTTCCT


chr2:103728071-103728571
  LENGTH = 500  COMBINED P-VALUE = 3.52e-02  E-VALUE =        7
  DIAGRAM: 369-[+1]-111

                                                                          [+1]
                                                                          2.6e-0
                                                                          AGCTGG
                                                                          ++++++
301  NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCAACTCTACCAGCTGG

     
     5
     GTGTGGCCGGGGGT
     + +++ + ++ +
376  GAGTGTTATCTTCCAGTAATTTGCCAAGAGGACAAACACACACAGCAAGAGAGACAGACGTCCGATGTGTGTTCT


chr5:105994747-105995247
  LENGTH = 500  COMBINED P-VALUE = 4.50e-02  E-VALUE =        9
  DIAGRAM: 93-[+2]-153-[-2]-194

                       [+2]
                       8.0e-05
                       TTGCTCCTCTCTTTTACCTCTTATCTCTGG
                        ++ +++++  +++ +++  ++  ++++++
76   TTAATACTCTGGAGGACAGGGGCTCTGGGCTTCTCTAGTTTCCTCTGCCTTGGAAGATTGTGGCCTTCCAGATGG

                                                        [-2]
                                                        4.7e-05
                                                        CCAGAGATAAGAGGTAAAAGAGAG
                                                        +  ++++++++   + ++++ +++
226  ATAATGAGCACGAGGCACCAGTCAGCCTTGAAGGAAAACTTGTGTCTGTTGAGGGAGATAAGTCTTCAGGATAAG

     
     
     GAGCAA
     +++++
301  CAGCCGTGTCTTACACATCTGAATTGTACACTTGGTTTTTATATGTTGAGGTGGATAAGGTACCCTAAACATCAT


chr17:84209565-84210065
  LENGTH = 500  COMBINED P-VALUE = 4.70e-02  E-VALUE =      9.4
  DIAGRAM: 64-[-2]-406

                                                                     [-2]
                                                                     1.6e-05
                                                                     CCAGAGATAAG
                                                                     + + +++ +++
1    CAAAGCCTCTCCTTCCGTGTCTCACCCCTGTAGTGTTTCCTTTCCGGCTTTCAGGAGAGTGGAAAAAAAGAGAAG

     
     
     AGGTAAAAGAGAGGAGCAA
     ++++++ + ++++++ ++
76   AGAAAATGCAAAGAGTCACTTGAAGGTAGAAGGTGTTTAAATGAAGTCTGCTGCCTNNNNNNNNNNNNNNNNNNN


chr7:16507689-16508189
  LENGTH = 500  COMBINED P-VALUE = 4.78e-02  E-VALUE =      9.6
  DIAGRAM: 231-[+2]-239

           [+2]
           7.4e-05
           TTGCTCCTCTCTTTTACCTCTTATCTCTGG
           ++  +++ ++++ +  ++++++ +++ +++
226  GTAACCTGAGAGCCCCTCGCCGTCCCTTCTCTATGCCATAATGGTTCAGTCCTCAGGGCGGTGGCTCGAGGCAGA

********************************************************************************


CPU: Timothys-iMac.rd.unr.edu
Time 0.041 secs.

mast -oc results/mast23 -nostatus meme/meme.Klf1-200.cd.oops.xml common/Klf1-200.fa
