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16 lines
659 B
Markdown
16 lines
659 B
Markdown
# Known Issues
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## Numerical performance for CUDA Capability 7.x GPUs
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All CUDA Capability 7.x GPUs (e.g. V100) produce obviously bad output, with lots
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of clashing residues (the clashes cause a ranking score of -99 or lower), unless
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the environment variable `XLA_FLAGS` is set to include
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`--xla_disable_hlo_passes=custom-kernel-fusion-rewriter`.
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## Incorrect handling of two-letter atoms in SMILES ligands
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Between commits https://github.com/google-deepmind/alphafold3/commit/f8df1c7 and
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https://github.com/google-deepmind/alphafold3/commit/4e4023c, AlphaFold 3
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handled incorrectly any two-letter atoms (e.g. Cl, Br) in ligands defined using
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SMILES strings.
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